Mir-BART1 microRNA precursor family

mir-BART1 microRNA precursor family
Predicted secondary structure and sequence conservation of mir-BART1
Identifiers
Symbolmir-BART1
RfamRF00363
miRBaseMI0001067
miRBase familyMIPF0000325
Other data
RNA typeGene; miRNA
Domain(s)Viruses
GOGO:0035195 GO:0035068
SOSO:0001244
PDB structuresPDBe

The mir-BART1 microRNA precursor is found in Human herpesvirus 4 (Epstein–Barr virus) and Cercopithicine herpesvirus 15. mir-BART1 is found in all stages of infection but expression is significantly elevated in the lytic stage. In Epstein-Barr virus, mir-BART1 is found in the intronic regions of the BART (Bam HI-A region rightward transcript) gene whose function is unknown.[1] The mature sequence is excised from the 5' arm of the hairpin.[2]

References

  1. ^ Qureshi A, Thakur N, Monga I, Thakur A, Kumar M (1 January 2014). "VIRmiRNA: a comprehensive resource for experimentally validated viral miRNAs and their targets". Database. 2014: bau103. doi:10.1093/database/bau103. PMC 4224276. PMID 25380780.
  2. ^ Pfeffer S, Zavolan M, Grässer FA, Chien M, Russo JJ, Ju J, John B, Enright AJ, Marks D, Sander C, Tuschl T (April 2004). "Identification of virus-encoded microRNAs". Science. 304 (5671): 734–6. doi:10.1126/science.1096781. PMID 15118162. S2CID 25287167.


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