Mir-166 microRNA precursor

mir-166 microRNA precursor
Predicted secondary structure and sequence conservation of mir-166
Identifiers
Symbolmir-166
RfamRF00075
miRBaseMI0000201
miRBase familyMIPF0000004
Other data
RNA typeGene; miRNA
Domain(s)Eukaryota
GOGO:0035195 GO:0035068
SOSO:0001244
PDB structuresPDBe

The plant mir-166 microRNA precursor is a small non-coding RNA gene. This microRNA (miRNA) has now been predicted or experimentally confirmed in a wide range of plant species.[1] microRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product.[2] In this case the mature sequence comes from the 3' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences.[3] The mature products are thought to have regulatory roles through complementarity to messenger RNA.

References

  1. ^ "miRNA gene family: MIR166". mirBASE. University of Manchester. Retrieved 5 September 2011.
  2. ^ Ambros V (December 2001). "microRNAs: tiny regulators with great potential". Cell. 107 (7): 823–6. doi:10.1016/S0092-8674(01)00616-X. PMID 11779458.
  3. ^ Reinhart BJ, Weinstein EG, Rhoades MW, Bartel B, Bartel DP (July 2002). "MicroRNAs in plants". Genes & Development. 16 (13): 1616–26. doi:10.1101/gad.1004402. PMC 186362. PMID 12101121.
Stub icon

This molecular or cell biology article is a stub. You can help Wikipedia by expanding it.