Mir-194 microRNA precursor family

mir-194 microRNA precursor family
Predicted secondary structure and sequence conservation of mir-194
Identifiers
Symbolmir-194
RfamRF00257
miRBaseMI0000488
miRBase familyMIPF0000055
Other data
RNA typeGene; miRNA
Domain(s)Eukaryota
GOGO:0035195 GO:0035068
SOSO:0001244
PDB structuresPDBe

In molecular biology, miR-194 microRNA precursor is a small non-coding RNA gene that regulated gene expression. Its expression has been verified in mouse (MI0000236, MI0000733)[1] and in human (MI0000488, MI0000732).[2] mir-194 appears to be a vertebrate-specific miRNA and has now been predicted or experimentally confirmed in a range of vertebrate species (MIPF0000055). The mature microRNA is processed from the longer hairpin precursor by the Dicer enzyme. In this case, the mature sequence is excised from the 5' arm of the hairpin.

See also

References

  1. ^ Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T (Feb 2003). "New microRNAs from mouse and human". RNA. 9 (2): 175–9. doi:10.1261/rna.2146903. PMC 1370382. PMID 12554859.
  2. ^ Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ (Oct 2003). "Reduced accumulation of specific microRNAs in colorectal neoplasia". Molecular Cancer Research. 1 (12): 882–91. PMID 14573789.


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