P2RY10

P2RY10
Identifiers
Aliases	P2RY10, LYPSR2, P2Y10, purinergic receptor P2Y10, P2Y receptor family member 10
External IDs	OMIM: 300529; MGI: 1926076; HomoloGene: 8717; GeneCards: P2RY10; OMA:P2RY10 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	78,963,727 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	106,148,580 bp
RNA expression pattern
	Top expressed in
	lymph node; ; epithelium of nasopharynx; ; blood; ; granulocyte; ; appendix; ; spleen; ; epithelium of colon; ; bone marrow; ; superficial temporal artery; ; bone marrow cells;
	Top expressed in
	mesenteric lymph nodes; ; thymus; ; spleen; ; blood; ; lumbar spinal ganglion; ; subcutaneous adipose tissue; ; white adipose tissue; ; pharynx; ; bone marrow; ; mammary gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled purinergic nucleotide receptor activity; signal transducer activity; G protein-coupled receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane;
Biological process	signal transduction; G protein-coupled purinergic nucleotide receptor signaling pathway; positive regulation of Rho protein signal transduction; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	27334
	78826
	ENSG00000078589
	ENSMUSG00000050921
	O00398
	Q8BFU7
	NM_014499; NM_198333; NM_001324218; NM_001324221; NM_001324225
	NM_172435; NM_001357810
	NP_001311147; NP_001311150; NP_001311154; NP_055314; NP_938147
	NP_766023; NP_001344739
	Wikidata
View/Edit Human	View/Edit Mouse

Putative P2Y purinoceptor 10 is a protein that, in humans, is encoded by the P2RY10 gene.^[5]^[6]^[7]

Function

The protein encoded by this gene belongs to the family of G-protein coupled receptors that is preferentially activated by adenosine and uridine nucleotides. Two alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000078589 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000050921 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Adrian K, Bernhard MK, Breitinger HG, Ogilvie A (June 2000). "Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1492 (1): 127–38. doi:10.1016/S0167-4781(00)00094-4. PMID 11004484.
^ Ralevic V, Burnstock G (September 1998). "Receptors for purines and pyrimidines". Pharmacological Reviews. 50 (3): 413–92. PMID 9755289.
^ ^a ^b "Entrez Gene: P2RY10 purinergic receptor P2Y, G-protein coupled, 10".