GPR149

GPR149
Identifiers
Aliases	GPR149, IEDA, PGR10, G protein-coupled receptor 149, R35
External IDs	MGI: 2443628; HomoloGene: 16359; GeneCards: GPR149; OMA:GPR149 - orthologs
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q25.2 Start 154,334,943 bp[1] End 154,430,190 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 E1 Start 62,436,498 bp[2] End 62,512,561 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle nucleus accumbens caudate nucleus putamen Pituitary Gland prefrontal cortex superior frontal gyrus anterior pituitary Hypothalamus primary visual cortex Top expressed in lumbar spinal ganglion secondary oocyte zygote primary oocyte ventromedial nucleus olfactory tubercle embryo trigeminal ganglion embryo facial motor nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function neuropeptide binding G protein-coupled receptor activity signal transducer activity melanin-concentrating hormone receptor activity peptide binding Cellular component integral component of membrane neuron projection plasma membrane integral component of plasma membrane membrane Biological process G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger negative regulation of ovulation G protein-coupled receptor signaling pathway neuropeptide signaling pathway preantral ovarian follicle growth antral ovarian follicle growth signal transduction chemical synaptic transmission Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 344758 229357 Ensembl ENSG00000174948 ENSMUSG00000043441 UniProt Q86SP6 Q3UVY1 RefSeq (mRNA) NM_001038705 NM_177346 NM_001356525 RefSeq (protein) NP_001033794 NP_796320 NP_001343454 Location (UCSC) Chr 3: 154.33 – 154.43 Mb Chr 3: 62.44 – 62.51 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 149 is a protein that in humans is encoded by the GPR149 gene.[5][6]

References

1. GRCh38: Ensembl release 89: ENSG00000174948 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000043441 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Vassilatis DK, Hohmann JG, Zeng H, Li F, Ranchalis JE, Mortrud MT, Brown A, Rodriguez SS, Weller JR, Wright AC, Bergmann JE, Gaitanaris GA (Apr 2003). "The G protein-coupled receptor repertoires of human and mouse". Proc Natl Acad Sci U S A. 100 (8): 4903–8. Bibcode:2003PNAS..100.4903V. doi:10.1073/pnas.0230374100. PMC 153653. PMID 12679517.
6. "Entrez Gene: GPR149 G protein-coupled receptor 149".