Receptor adrenérgico alfa 1A

O receptor adrenérgico alfa 1A (adrenorreceptor α1A). também conhecido como ADRA1A, é um receptor adrenérgico alfa 1 e também denota o gene humano que o codifica.[1] É encontrado no trato urinário e na próstata.[2]

A tansulosina é um fármaco antagonista seletivo desse receptor, sendo utilizado para o tratamento de hiperplasia benigna de próstata. Diminui a obstrução do fluxo urinário (melhorando os sintomas obstrutivos) através do relaxamento da musculatura lisa na próstata e na uretra.[2]

Referências

  1. ↑ «α1A-adrenoceptor» (em inglês). IUPHAR DATABASE. Consultado em 1 de julho de 2010 
  2. ↑ a b WHALEN, KAREN et. al (2016). Farmacologia Ilustrada. Porto Alegre: Artmed. 80 páginas 

Leitura de apoio

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