Colonization of Propionibacterium acnes is one of factors that causes acne vulgaris. The present study was conducted to evaluate antiacne effect from cream of methanolic extract from stems and leaves of Impatiens balsamina L. towards Propionibacterium acnes, concentration that gives greatest antiacne effect and to evaluate physical and chemical properties of creams. Simplicia were extracted using soxhlet technique and methanol as solvent. Extract then formulated in cream in three variations of concentration as following 10%(F1), 15%(F2) and 20%(F3). The determination of antiacne effect was don…
Cigarette smoke is one of free radical source that can cause oxidative stress, emphysema, and inflamation on lung. Leaves of Premna cordifolia Linn. is one of antioxidant that can neutralize the free radical in body. The purpose of the research is to find the antioxidant activity of Premna cordifolia leaves in reducing lung’s damage and to find the effective dose that can reduce lung’s damage after exposure of cigarette smoke. Dried leaves of Premna cordifolia are maserated with ethanol 70%. Rats are divided into five groups, Group without treatment (CMC control), gro…
Propionibacterium acnes dan Staphylococcus epidermidis is an inflamation triggering bacterias in acne vulgaris. Plants that has been studied for antibacterial effect is Impatiens balsamina. Gel bases for acnes therapy are hydrophilic bases like HPMC (Hydroxypropyl methylcellulose) and carbopol. The aim of this study was to know the optimum combination of Carbopol and HPMC (Hydroxypropyl metylcellulose) in gel formulation that gives best antibacterial effect and to evaluate physical and chemical properties of gel. Extraction was performed by soxhlet method with methanol as solvent. The design o…
Impatiens balsamina Linn has been proven through various studies to have pharmacological benefits. Yet there was no research data regarding the toxicity of these plants. The purpose of this study was to determine the acute toxicity of symptoms that occur after oral administration of ethyl acetate fraction from stems and leaves of Impatiens balsamina Linn, determine the LD50 values ​​and toxicity category compounds in the fraction. This study employed OECD (Organization for Economic, Cooperation and Development) 425 method. Parameters observed qualitatively through the observation…
Tumbuhan Tembelekan dianggap masyarakat sebagai pengganggu atau gulma karena pertumbuhannya yang dahsyat merambat ke segala arah sehingga mengganggu pada kegiatan pembukaan lahan. Manfaat tradisional daun tumbuhan ini dikenal oleh berbagai suku di Indonesia, tetapi hanya sebagai obat luka yang tidak menarik karena obat luka tergolong obat murah di pasaran. Potensi botani yang tampak terhadap tumbuhan Tembelekan adalah pertumbuhannya yang dahsyat sehingga jika memiliki manfaat ekonomi menjadi sangat potensial ditinjau dari penyediaan bahan baku. Beberapa penelitian ilmiah telah dilakukan terhad…
Research has been conducted with a purpose to find out the potential of the extracts of leaves Ageratum conyzoides and Artocarpus champedan as an antioxidant compared with vitamin C. Research was done by infused extraction method, and combination both of them with a partition 1:1, 1:2, 2:1. Keywords: Ageratum conyzoides L, Artocarpus champeden, DPPH, antioxidant ABSTRAK Kombinasi ekstrak daun bandotan (Ageratum conyzoides L) dan daun cempedak (Artocarpus champeden) memiliki aktivitas antioksidan harga IC50 yang kuat dengan menggunakan kombinasi daun bandotan : daun cempedak perban…
A study concerning the characteristics and Analysis of Drug Related Problems (DRPs) Patients with Tuberculosis Patients in Public Health Center (PHC) Temindung, Samarinda in East Kalimantan. The study was conducted using a prospective approach to the study of data sources in the form of primary data and secondary data. The primary data source is data from interviews with patients and through the provision of questionnaires and secondary data in this research is a Tuberculosis patient medical record data. Data collection was performed by analyzing the accuracy of the DRPs categories of accuracy…
The research of Immunoglobulin M (IgM) activity of Theobroma cacao peel extract has been done to 20 rats. The parameter is agglutination between serum of rats and antigen. Rats were grouped to 4 group, which are group of negative control and 3 groups as experiment groups those given by extract in 250, 500 and 700 mg doses of rats. On the first day was given SDMK 2% by Intraperitonial and after 5 day the serum taken and tested. The data of agglutination then analyzed by Anova. The experiment showed that Theobroma cacao peel extract has activity as immunostimulant in 500 mg doses of rats effecti…
Research on manufacturing the kapur (Dryobalanopsspp.) particle board has been conducted using the mixture of clover leaf oil by products andtannin after being mixed with phenol and formaldehyde as adhesives. Particle board was prepared by molding process while pressing and heating. Particle board measured by usingSNI 01-2105-1991 have physical properties i.e. density, water content, thickness swelling meet the standard whereas the mechanical properties i.e. modulus of elasticity, modulus of rupture, internal bond strength, and screw holding strength do not meet the standard. Ultra-violet cure…
Teknik iradiasi sinar gamma dapat meningkatkan frekuensi dan memperluas spektrum mutasi makro namun belum banyak dikaji pengaruhnya terhadap mutasi mikro pada karakter kuantitatif dalam populasi termutasi. Penelitian ini bertujuan untuk mempelajari pengaruh perlakuan teknik iradiasi terhadap keragaman genetik dan heritabilitas karakter agronomi gandum pada generasi M2. Penelitian ini dilaksanakan dari bulan Juli sampai November 2014 di kebun percobaan Cibadak, Balai Besar Penelitian dan Pengembangan Bioteknologi dan Sumber Daya Genetik Pertanian, Kementerian Pertanian. Benih tiga galur gandum …
The synthesis and effect of gamma irradiation on characteristics of microbial cellulose membrane have been evaluated. Microbialcellulose gel (nata de coco) was produce using bacteria Acetobacter xylinum incubated in bacterial growth medium containing coconut water as a micro nutrient source. Microbial cellulose membrane was prepared using mould compression at 120°C for 5 minutes. The membranes were irradiated using gamma rays with doses of 25 and 50 kGy respectively at dose rate of 10 kGy/h. Several parameters such as water absorption, surface morphology, thermal and mechanical properties o…
Tapioka dapat digunakan sebagai medium pertumbuhan isolat khamir karena mengandung karbohidrat tinggi. Sterilisasi dengan iradiasi sinar gamma menghasilkan senyawa senyawayang lebih sederhana dan bersifat toksik. Tujuan dari percobaan ini adalah untuk mengetahui pengaruh dosis iradiasi terhadap sifat fisik dan kimia serta pertumbuhan isolat khamir R1 dan R2 serta isolat mutan R110 dan R210. Dosis yang digunakan adalah 10, 20, dan 30 kGy. Hasil percobaan menunjukkan bahwa terjadiperubahan warna yang semakin gelap dan granula pati semakin kecil sebanding dengan meningkatnya dosis, sedangkan seca…
Varietas Mutiara 3 merupakan salah satu varietas unggul kedelai yang dihasilkan melalui teknik mutasi radiasi. Pengembangan varietas kedelai unggul nasional harus didukung oleh teknologi pemupukan seperti pemanfaatan teknologi pupuk hayati. Penggunaan pupuk hayati rhizobium perlu memperhitungkan aspek kesesuaian antara bakteri Rhizobium yang diaplikasikan dengan varietas tanaman kedelai. Penelitian ini dilakukan untuk mengetahui pengaruh kombinasi rhizobium dan mikroba pelarut fosfat terhadap tanaman kedelai varietas Mutiara 3. Seleksi isolat rhizobium dilakukan dengan melihat pola dan kec…
Penelitian ini bertujuan untuk meningkatkan aktivitas enzim selulase dan produksi glukosa dalam substrat jerami padi dengan fungi Aspergillus niger yang dipapari sinar gamma Chamber 4000A. Kaldu kentang dektrosa (PDB), garam mineral dengan substrat jerami padi 0 dan 5% berat/volum digunakan sebagai medium cair. Fungi Aspergillus niger dalam media agar miring (slent) dipapari dengan iradiasi gamma pada dosis 0 (kontrol),125, 250, 375, 500 dan 625 Gy. Fungi Aspergillus niger yang dipapari sinar gamma 500 Gy memiliki aktivitas selulase lebih tinggi (2,5 kali) dibanding kontrol (0 Gy) yaitu 2,…
Telah diketahui bahwa iradiasi gamma dosis 90 Gy padakepompong lalat buah Bactrocera carambolae (Drew & Hancock) dapat menyebabkan kemandulan pada lalat jantan dewasa, namun belum banyak diinformasikan penyebab terjadinya kemandulan. Untuk mengetahui hal tersebut, telah diteliti perubahan morfologisdan histologis yang terjadi pada alat reproduksi jantan (testis) lalat mandul sebagai akibat iradiasi gamma. Kepompong umur 9 hari diradiasi dengan sinar gamma 90 Gy dan lalat jantan umur 7 hari dan 14 hari yang muncul dari kepompong dibedah, untuk diisolasi testisnya. Testis dari lalat iradiasi dan…
Umbi sarang semut (Myrmecodia pendans Merr. & Perry) memiliki aktivitas sitotoksik. Salah satu usaha pengawetan simplisia umbi sarang semut dilakukan dengan iradiasi gamma. Penelitian ini bertujuan untuk mempelajari pengaruh iradiasi gamma pada sitotoksisitas dan profil kromatogram fraksi aktif dari umbi sarang semut. Serbuk kering umbi sarang semut diiradiasi gamma dengan beberapa macam dosis radiasi yaitu : 0 (kontrol); 5; 7,5; 10; dan 15 kGy. Percobaan dilakukan dengan dua kali ulangan untuk masing-masing dosis. Setelah iradiasi, serbuk dimaserasi bertahap berdasarkan tingkat kepolarannya d…
Serangan penyakit malaria di Indonesia terus meningkat. Di lain pihak, penyebab penyakit ini yaitu Plasmodium falciparum telah resisten terhadap obat malaria yang selama ini digunakan. Artemisinin, dari tanaman artemisia telah diteliti dapat mengendalikan malaria. Permasalahan yang dihadapi adalah kandungan artemisinin dari Artemisia annua yang ditanamdi Indonesia masih sangat rendah, yaitu berkisar 0.1 — 0.5 %. Peningkatan keragaman genetik artemisia dengan menggunakan iradiasi sinar gamma merupakan metode alternative untukmengatasi masalah tersebut. Pada penelitian sebelumnya telah di…
Pengukuran profil 210Pb unsupported dan logam berat Zn, Cr pada sedimen di Muara Cisadane telah dilakukan pada tahun 2002. Kedua sedimen core diambil masing-masing di Muara Tanjung Burung dan Muara Tiang Sampan. Profil 210Pb unsupported dapat digunakan untuk menghitung laju pengendapan dan untuk menghitung fluks deposisi Zn dan Cr berdasarkan siklus waktu 5 tahunan. Laju pengendapan sedimen kering di Muara Tanjung Burung adalah 4,142 gr/cm2/th, 2,518 gr/cm2/th dan 1,27 gr/cm2/th masing-masing untuk periode 1997- 2002, 1992-1997 dan 1987-1992. Laju pengendapan pada Muara Tiang Sampan sebesar 3,…
Language is used not only for communication but also to reflect personality as well as to construct identity. The aim of this study is to examine Mikhailâs personal identity construction through his language use. Therefore, the labels attached to him and his stancetakings are investigated. In conducting the study, the writer applies Discourse Analysis. Descriptive research is used in order to identify, classify, and describe his utterances which contain the use of label and stancetaking. The findings reveal that he is a kind of arrogant person based on the values of the labels given by se…
In the Victorian era, the existence of governess held unique position and became a social phenomenon in England. The governess became a popular figure in fiction. Many authors of governess novels drew on their own experience as a governess. Among these authors is Anne Bronte. In her first novel Agnes Grey, she depicted the life of governess throughout its female main character named Agnes Grey. This thesis focuses on analyzing that female main character and her struggle of being a governess. The aims of the thesis are to examine the motive that leads Agnes Grey to be a governess and to reveal …