Metaloproteinase matriks-9

Metaloproteinase matriks-9 (bahasa Inggris: 92-kDa gelatinase; matrix metalloproteinase 9; type V collagenase; 92-kDa type IV collagenase; macrophage gelatinase; 95 kDa type IV collagenase/gelatinase; gelatinase B, Type V collagenase, collagenase IV; collagenase type IV; gelatinase MMP 9; ; matrix metalloproteinase 9; type IV collagen metalloproteinase, MMP-9, EC 3.4.24.35) merupakan enzim dengan aktivitas proteolitik pada gelatin tipe I dan V, dan kolagen tipe IV dan V.[1][2]

Dari penelitian di Eropa, kelainan genetika pada MMP-9 merupakan risiko tertinggi terserang leukaemia limfositik kronis, dan memiliki pola reaksi serologikal abnormal terhadap virus Epstein-Barr.[3]

senyawa inhibitor MMP-9 adalah matlistatin A dan matlistatin B.[4]


Rujukan

  1. ^ (Inggris) "EC 3.4.24.35". Queen Mary University of London. Diakses tanggal 2010-12-07. 
  2. ^ (Inggris) "ENZYME entry: EC 3.4.24.35". Swiss Institute of Bioinformatics. Diakses tanggal 2010-12-07. 
  3. ^ (Inggris) "Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP-9) and tumour protein 73 (TP73) interact with Epstein Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph". CIBERESP, IDIBELL; Casabonne D, Reina O, Benavente Y, Becker N, Maynadie' M, Foretova L, Cocco P, Gonzalez-Neira A, Nieters A, Boffetta P, Middeldorp JM, de Sanjose S. Diakses tanggal 2010-12-07. 
  4. ^ (Inggris) "Summary for peptidase M10.004: matrix metallopeptidase-9". Wellcome Trust Sanger Institute. Diakses tanggal 2010-12-07. 

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