乙基沙林

乙基沙林
IUPAC名
Propan-2-yl ethylphosphonofluoridate
别名 GE、EA-1209、
TL-1620、T-2109、
异丙基-P-乙基膦酰氟
识别
CAS号 1189-87-3  checkY
PubChem 65566
ChemSpider 59009
SMILES
 
  • CCP(=O)(OC(C)C)F
性质
化学式 C5H12FO2P
摩尔质量 154.12 g·mol−1
密度 1.1012 g·cm−3（20 °C）[1]
沸点 74 °C（16 torr）[2]
91~93 °C（40 torr）[1]
170 °C
蒸氣壓 1.97 mmHg
危险性
主要危害 剧毒
致死量或浓度：
LD50（中位剂量）
 690 mg/kg（鼠，腹膜内）[3]
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

乙基沙林（GE），又称EA-1209、[4] TL-1620或T-2109，[5]是G系列中的一种有机磷神经性毒剂。它是沙林的乙氟膦酸类似物。[6][7]有文献对其谱图及反应性做了研究。[8][9]它的毒性是沙林的八分之一，但持久性比沙林高2-3倍。[10][11]

参考文献

  1. ^ 1.0 1.1 Drozd, G. I.; Ivin, S. Z.; Kulakova, V. N.; Sheluchenko, V. V. Alkoxyalkyl(aryl)​difluoromonohydridophosphoranes. Zhurnal Obshchei Khimii, 1968. 38 (3): 576-581. ISSN 0044-460X.
  2. ^ R. Schmutzler. 868. Phosphorus–fluorine chemistry. Part VIII. Some comments on the “group shift theory,” as applied to the 31 P nuclear magnetic resonance spectra of certain phosphorus fluorides. J. Chem. Soc. 1964, 0 (0): 4551–4557 [2022-03-02]. ISSN 0368-1769. doi:10.1039/JR9640004551 （英语）. 
  3. ^ ChemIDplus. [2022-03-01]. （原始内容存档于2022-03-01）. 
  4. ^ Physical properties of standard agents, candidate agents, and related compounds at several temperatures (PDF). [2022-03-01]. （原始内容 (PDF)存档于2017-02-26）. 
  5. ^ Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. [2022-03-01]. （原始内容存档于2021-12-12）. 
  6. ^ Handbook of chemical and biological warfare agents 2nd. CRC Press. ISBN 9780849314346. 
  7. ^ Compendium of chemical warfare agents. Springer. 2010-10-18. ISBN 9780387346267. 
  8. ^ David J. McGarvey, John R. Stuff, Barry R. Williams, H. Dupont Durst. Vapor-Phase Infrared Spectral Study of Analogs of the Nerve Agent Sarin. Spectroscopy Letters. 2000-11, 33 (6): 795–819 [2022-03-02]. ISSN 0038-7010. doi:10.1080/00387010009350158 （英语）. 
  9. ^ Neimysheva, A. A.; Knunyants, I. L. Spectral characteristics and reactivity of carboxylic, phosphonic, phosphinic, and sulfonic acid halides. Reaktsionnaya Sposobnost Organicheskikh Soedinenii, 1968. 5 (1): 127-140. ISSN 0375-9520.
  10. ^ Franks, S. Manual of Military Chemistry. Volume 1. Chemistry of Chemical Warfare Agents.. Assistant Chief of Staff for Intelligence (Army), Washington, D.C. 1968: 247 [2024-01-03]. （原始内容存档于2023-05-29）. 
  11. ^ Department Of The Army Office Of The Chief, Chemical Corps. CMLWH.  A1.13 - RLF/TSE/5190/blac. 17 February 1948.