PRSS2

PRSS2
معرفات
أسماء بديلة PRSS2, TRY2, TRY8, TRYP2, protease, serine 2, serine protease 2
معرفات خارجية الوراثة المندلية البشرية عبر الإنترنت 601564 MGI: MGI:102759 HomoloGene: 122141 GeneCards: 5645
تماثلات متسلسلة
أنواع الإنسان الفأر
أنتريه 5645 22072
Ensembl ‏ENSG00000275896;db=core ENSG00000282049، ‏ENSG00000275896 ENSMUSG00000057163
يونيبروت
RefSeq (رنا مرسال.)

‏NM_001303414، ‏NM_002770 NR_130149، ‏NM_001303414، ‏NM_002770

NM_009430

RefSeq (بروتين)

‏NP_002761 NP_001290343، ‏NP_002761

NP_033456

الموقع (UCSC n/a Chr 6: 41.5 – 41.5 Mb
بحث ببمد [1] [2]
ويكي بيانات
اعرض/عدّل إنساناعرض/عدّل فأر

PRSS2‏ (Serine protease 2) هوَ بروتين يُشَفر بواسطة جين PRSS2 في الإنسان.[1]

الوظيفة

الأهمية السريرية

المراجع

  1. ^ "Entrez Gene: Protease, serine, 2 (trypsin 2)". مؤرشف من الأصل في 2016-03-18.

قراءة متعمقة

  • Williams SJ، Gotley DC، Antalis TM (يوليو 2001). "Human trypsinogen in colorectal cancer". International Journal of Cancer. ج. 93 ع. 1: 67–73. DOI:10.1002/ijc.1304. PMID:11391623.
  • Mayumi T، Inui K، Maetani I، Yokoe M، Sakamoto T، Yoshida M، Ko S، Hirata K، Takada T (أغسطس 2012). "Validity of the urinary trypsinogen-2 test in the diagnosis of acute pancreatitis". Pancreas. ج. 41 ع. 6: 869–75. DOI:10.1097/MPA.0b013e3182480ab7. PMID:22481290.
  • "PRSS1-Related Hereditary Pancreatitis". GeneReviews®. 1993. PMID:22379635.
  • Ahmed M، Forsberg J، Bergsten P (2005). "Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry". Journal of Proteome Research. ج. 4 ع. 3: 931–40. DOI:10.1021/pr050024a. PMID:15952740.
  • Vilen ST، Suojanen J، Salas F، Risteli J، Ylipalosaari M، Itkonen O، Koistinen H، Baumann M، Stenman UH، Sorsa T، Salo T، Nyberg P (أكتوبر 2012). "Trypsin-2 enhances carcinoma invasion by processing tight junctions and activating ProMT1-MMP". Cancer Investigation. ج. 30 ع. 8: 583–92. DOI:10.3109/07357907.2012.716467. PMID:22909050.
  • Lempinen M، Isoniemi H، Mäkisalo H، Nordin A، Halme L، Arola J، Höckerstedt K، Stenman UH (نوفمبر 2007). "Enhanced detection of cholangiocarcinoma with serum trypsinogen-2 in patients with severe bile duct strictures". Journal of Hepatology. ج. 47 ع. 5: 677–83. DOI:10.1016/j.jhep.2007.05.017. PMID:17640760.
  • Galey D، Becker K، Haughey N، Kalehua A، Taub D، Woodward J، Mattson MP، Nath A (يونيو 2003). "Differential transcriptional regulation by human immunodeficiency virus type 1 and gp120 in human astrocytes". Journal of Neurovirology. ج. 9 ع. 3: 358–71. DOI:10.1080/13550280390201119. PMID:12775419.
  • Baptista AM، Jonson PH، Hough E، Petersen SB (سبتمبر 1998). "The origin of trypsin: evidence for multiple gene duplications in trypsins". Journal of Molecular Evolution. ج. 47 ع. 3: 353–62. DOI:10.1007/PL00006393. PMID:9732462.
  • Gao J، Zhu F، Lv S، Li Z، Ling Z، Gong Y، Jie C، Ma L (يونيو 2010). "Identification of pancreatic juice proteins as biomarkers of pancreatic cancer". Oncology Reports. ج. 23 ع. 6: 1683–92. DOI:10.3892/or_00000812. PMID:20428826.

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