SGK2

SGK2
Identifiers
AliasesSGK2, H-dJ138B7.2, serine/threonine kinase 2, serum/glucocorticoid regulated kinase 2
External IDsOMIM: 607589; MGI: 1351318; HomoloGene: 8446; GeneCards: SGK2; OMA:SGK2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_170693
NM_001199264
NM_016276

NM_001291152
NM_001291154
NM_013731

RefSeq (protein)

NP_001186193
NP_057360
NP_733794

NP_001278081
NP_001278083
NP_038759

Location (UCSC)Chr 20: 43.56 – 43.59 MbChr 2: 162.83 – 162.86 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Serine/threonine-protein kinase Sgk2 is an enzyme that in humans is encoded by the SGK2 gene.[5][6]

This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase (PI3K), which is also true for SGK. Two alternate transcripts encoding two different isoforms have been described.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000101049Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017868Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kobayashi T, Deak M, Morrice N, Cohen P (Jan 2000). "Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase". Biochem J. 344 (1): 189–97. doi:10.1042/0264-6021:3440189. PMC 1220630. PMID 10548550.
  6. ^ a b "Entrez Gene: SGK2 serum/glucocorticoid regulated kinase 2".

Further reading