Gamithromycin
Medication
Gamithromycin Trade names Zactran Other names ML-1709460, ML-460 License data
Routes of administration Subcutaneous Drug class Macrolide antibiotic ATCvet code Legal status
(2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,8,10,12,14-hexamethyl-7-propyl-1-oxa-7-azacyclopentadecan-15-one
CAS Number PubChem CID DrugBank ChemSpider UNII KEGG ChEBI ChEMBL CompTox Dashboard (EPA ) ECHA InfoCard 100.123.704 Formula C 40 H 76 N 2 O 12 Molar mass 777.050 g·mol−1 3D model (JSmol )
[H][C@@]1(C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)O[C@H]1[C@H](C)[C@@H](O[C@]2([H])O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)N(CCC)C[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]1C
InChI=1S/C40H76N2O12/c1-15-17-42-21-22(3)33(44)40(11,48)29(16-2)52-36(46)26(7)32(53-30-20-39(10,49-14)34(45)27(8)51-30)25(6)35(38(9,47)19-23(42)4)54-37-31(43)28(41(12)13)18-24(5)50-37/h22-35,37,43-45,47-48H,15-21H2,1-14H3/t22-,23+,24+,25-,26+,27-,28-,29+,30-,31+,32-,33+,34-,35+,37-,38+,39+,40+/m0/s1
Key:VWAMTBXLZPEDQO-UZSBJOJWSA-N
Gamithromycin , sold under the brand name Zactran , is a veterinary medication used for the treatment of cattle, pigs, and sheep.[ 3] [ 4] [ 5] It is a macrolide antibacterial.[ 3] [ 4] It is a 7a-azalide .[ 6]
It was approved for veterinary use in the European Union in 2008.[ 3] [ 4]
Veterinary uses
In the EU, gamithromycin is indicated for the treatment and prevention of bovine respiratory disease in cattle, swine respiratory disease in pigs, and infectious pododermatitis (foot rot) in sheep.[ 3] [ 4] [ 6]
In the US, gamithromycin is indicated for the treatment of bovine respiratory disease in cattle.[ 1]
References
External links