Streptogramin

Streptogramins are a class of antibiotics.[1]

Streptogramins are effective in the treatment of vancomycin-resistant Staphylococcus aureus (VRSA) and vancomycin-resistant Enterococcus (VRE), two of the most rapidly growing strains of multidrug-resistant bacteria. They fall into two groups: streptogramin A and streptogramin B.[2]

Members include:

• Quinupristin/dalfopristin
• Pristinamycin
• Virginiamycin
• NXL 103, an experimental streptogramin in clinical trials for the treatment of respiratory tract infections.[3]

References

1. University of Leeds: Antimicrobial Chemotherapy Archived 2007-04-28 at the Wayback Machine
2. "Streptogramin - an overview | ScienceDirect Topics". www.sciencedirect.com. Retrieved 2024-10-06.
3. Boucher, H. W.; Talbot, G. H.; Bradley, J. S.; Edwards, J. E.; Gilbert, D; Rice, L. B.; Scheld, M; Spellberg, B; Bartlett, J (2009). "Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America". Clinical Infectious Diseases. 48 (1): 1–12. doi:10.1086/595011. PMID 19035777.