At the University of Minnesota, Evans graduated in 1935 with a B.S., in 1937 with an M.D., and in 1942 with a Ph.D. in bacteriology.[1] His Ph.D. thesis is entitled A study of herpetic infections of the nervous system.[2] From 1938 to 1941 he was employed by the Bureau of Biological Survey and, simultaneously, was an assistant scientist and later an associate scientist at the University of Minnesota. From 1941 to 1942 he was a research fellow at the University of Rochester. In the department of bacteriology of the University of Minnesota, he was from 1942 to 1944 an assistant professor and from 1944 to 1946 an associate professor.[1] In the department of bacteriology of Seattle's University of Washington, he was a full professor from 1946 until his retirement as professor emeritus after 36 years of professorial service. He chaired the department from 1946 to 1970.[3] He served as associate director of the Fred Hutchinson Cancer Research Center for a few years in its formative phase.[4]
Evans was from 1951 to 1955 a member of the editorial board for the Journal of Bacteriology and from 1954 to 1956 an associate editor for the journal Virology.[4] He was the author of coauthor of more than 200 scientific publications.[3][4] The 1954 Nobel Prize lecture by John Enders mentions the importance of the collaborative research of Evans and Robert Gladding Green (1895–1947) in demonstrating that the poliomyelitis viruses are not strict neurotropes. The lecture also cites two pages coauthored by Evans with Wayne Maurice Smith (1922–2019) and Velma C. Chambers (1909–2003).[5][6][7][8]
Although best known for his research on the growth of poliomyelitis virus in cell and tissue culture, Evans also did research on papillomavirus infections in rabbits,[4] population cycles in snowshoe hares,[9] encephalitis in foxes, canine distemper, and viral infections of intraocular tissues.[1] In the later years of his career, he did research on the ecology of skin microflora and its role in the etiology and pathogenesis of disease.[4]
In December 1939 he married Allie Ann Christman (1917–2014).[11] Nicholas J. Evans, one of their two sons, died in 1948 at the age of six. Upon his death, Charles A. Evans was survived by his widow, one son, two daughters, and six grandchildren.[12] In his honor, the University of Washington's Department of Microbiology awards the Dr. Charles A. and Allie Ann Evans Endowed Scholarship.[13]
Selected publications
Evans, Charles A. (1938). "Observations on Hibernating Bats with Especial Reference to Reproduction and Splenic Adaptation". The American Naturalist. 72 (742): 480–484. doi:10.1086/280802. S2CID84847373.
Evans, Charles A. (1947). "Does Poliomyelitis Virus Grow in Sewage?". Acta Medica Scandinavica. 126 (6): 541–545. doi:10.1111/j.0954-6820.1947.tb19041.x.
Hotta, Susumu; Evans, Charles A. (1956). "Cultivation of Mouse-Adapted Dengue Virus (Type 1) in Rhesus Monkey Tissue Culture". The Journal of Infectious Diseases. 98 (1): 88–97. doi:10.1093/infdis/98.1.88. JSTOR30094234. PMID13295630.
^ ab"Curriculum Vitae of Dr. Charles A. Evans". Use of Advisory Committees by the Food and Drug Administration: Hearings Before a Subcommittee of the Committee on Government Operations, House of Representatives, Ninety-third Congress, Second Session. U.S. Government Printing Office. 1975. pp. 303–309; with comprehensive list of publications{{cite book}}: CS1 maint: postscript (link)
^Smith, W. M.; Chambers, V. C.; Evans, C. A. (1950). "Growth of neurotropic viruses in extraneural tissues; preliminary report on the propagation of poliomyelitis virus (Lansing and Hof. Strains) in cultures of human testicular tissue". Northwest Med. 49 (6): 368–373. PMID15429981.
^Smith, W. M.; Chambers, V. C.; Evans, C. A. (1951). "Growth of Neurotropic Viruses in Extraneural Tissues IV. Poliomyelitis Virus in Human Testicular Tissue in vitro". Proc. Soc. Exp. Biol. Med. 76 (4): 696–700. doi:10.3181/00379727-76-18598. PMID14844315. S2CID11544626.
^Green, R. G.; Evans, C. A. (1940). "Studies on a Population Cycle of Snowshoe Hares on the Lake Alexander Area I. Gross Annual Censuses, 1932-1939". The Journal of Wildlife Management. 4 (2): 220–238. doi:10.2307/3795657. JSTOR3795657.