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猪冠状病毒（英語：Pig coronaviruses）指冠状病毒中可以感染猪的毒株，已知的有以下六株^[1]：


名稱	英文及簡稱	屬	發現年份	發現地點	近似病毒	感染組織	細胞受體	傳染途徑	症狀	來源
猪流行性腹泻病毒	porcine epidemic diarrhoea virus PEDV	甲	1978年	比利時	高頭蝠冠狀病毒512	消化道	AP-N	糞口	腹瀉、嘔吐（英语：Porcine epidemic diarrhoea）	^[2]^[3]
猪传染性胃肠炎病毒	transmissible gastroenteritis virus TGEV	甲	1946年	美國	貓冠狀病毒、犬冠狀病毒	消化道	AP-N與醣基	糞口	腹瀉、嘔吐	^[3]^[4]
猪呼吸道冠状病毒	porcine respiratory coronavirus PRCV	甲	1984年	比利時	猪传染性胃肠炎病毒	呼吸道	AP-N	空氣	肺部感染（輕微）	^[4]
猪急性腹泻综合征冠状病毒	Swine acute diarrhea syndrome coronavirus SADS-CoV	甲	2018年	中國廣東	菊頭蝠冠狀病毒HKU2	消化道	未知	糞口	腹瀉、嘔吐	^[5]
猪凝血性脑脊髓炎病毒	porcine haemagglutinating encephalomyelitis virus PHEV	乙	1971年	加拿大安大略	乙型冠狀病毒1型	神經、呼吸道	NCAM	接觸、飛沫	嘔吐、顫抖、蜷縮、共濟失調	^[6]^[7]^[8]
猪丁型冠状病毒	porcine deltacoronavirus PDCoV	丁	2012年	香港	麻雀冠狀病毒HKU17、鵪鶉冠狀病毒HKU30	消化道	AP-N	糞口	腹瀉	^[9]^[10]

参考文献

^ Domańska-Blicharz, Katarzyna; Woźniakowski, Grzegorz; Konopka, Bogdan; Niemczuk, Krzysztof; Welz, Mirosław; Rola, Jerzy; Socha, Wojciech; Orłowska, Anna; Antas, Marta; Śmietanka, Krzysztof; Cuvelier-Mizak, Beata. Animal coronaviruses in the light of COVID-19. Journal of Veterinary Research. 2020-08-02, 64 (3): 333–345. doi:10.2478/jvetres-2020-0050.
^ Banerjee A, Kulcsar K, Misra V, Frieman M, Mossman K. Bats and Coronaviruses.. Viruses. 2019, 11 (1). PMC 6356540 . PMID 30634396. doi:10.3390/v11010041.
^ ^3.0 ^3.1 Liu C, Tang J, Ma Y, Liang X, Yang Y, Peng G; et al. Receptor usage and cell entry of porcine epidemic diarrhea coronavirus.. J Virol. 2015, 89 (11): 6121–5. PMC 4442452 . PMID 25787280. doi:10.1128/JVI.00430-15.
^ ^4.0 ^4.1 Li F. Receptor recognition mechanisms of coronaviruses: a decade of structural studies.. J Virol. 2015, 89 (4): 1954–64. PMC 4338876 . PMID 25428871. doi:10.1128/JVI.02615-14.
^ Yu J, Qiao S, Guo R, Wang X. Cryo-EM structures of HKU2 and SADS-CoV spike glycoproteins provide insights into coronavirus evolution.. Nat Commun. 2020, 11 (1): 3070. PMC 7300015 . PMID 32555182. doi:10.1038/s41467-020-16876-4.
^ Li Z, Zhao K, Lan Y, Lv X, Hu S, Guan J; et al. Porcine Hemagglutinating Encephalomyelitis Virus Enters Neuro-2a Cells via Clathrin-Mediated Endocytosis in a Rab5-, Cholesterol-, and pH-Dependent Manner.. J Virol. 2017, 91 (23). PMC 5686734 . PMID 28956766. doi:10.1128/JVI.01083-17.
^ Mora-Díaz JC, Piñeyro PE, Houston E, Zimmerman J, Giménez-Lirola LG. Porcine Hemagglutinating Encephalomyelitis Virus: A Review.. Front Vet Sci. 2019, 6: 53. PMC 6402421 . PMID 30873421. doi:10.3389/fvets.2019.00053.
^ Lorbach JN, Wang L, Nolting JM, Benjamin MG, Killian ML, Zhang Y; et al. Porcine Hemagglutinating Encephalomyelitis Virus and Respiratory Disease in Exhibition Swine, Michigan, USA, 2015.. Emerg Infect Dis. 2017, 23 (7): 1168–1171. PMC 5512476 . PMID 28628449. doi:10.3201/eid2307.170019.
^ Woo, P. C. Y.; Lau, S. K. P.; Lam, C. S. F.; Lau, C. C. Y.; Tsang, A. K. L.; Lau, J. H. N.; Bai, R.; Teng, J. L. L.; Tsang, C. C. C.; Wang, M.; Zheng, B.-J.; Chan, K.-H.; Yuen, K.-Y. Discovery of Seven Novel Mammalian and Avian Coronaviruses in the Genus Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of Alphacoronavirus and Betacoronavirus and Avian Coronaviruses as the Gene Source of Gammacoronavirus and Deltacoronavirus. Journal of Virology. 2012, 86 (7): 3995–4008. ISSN 0022-538X. doi:10.1128/JVI.06540-11.
^ Boley PA, Alhamo MA, Lossie G, Yadav KK, Vasquez-Lee M, Saif LJ; et al. Porcine Deltacoronavirus Infection and Transmission in Poultry, United States1.. Emerg Infect Dis. 2020, 26 (2): 255–265. PMC 6986833 . PMID 31961296. doi:10.3201/eid2602.190346.

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[1] Domańska-Blicharz, Katarzyna; Woźniakowski, Grzegorz; Konopka, Bogdan; Niemczuk, Krzysztof; Welz, Mirosław; Rola, Jerzy; Socha, Wojciech; Orłowska, Anna; Antas, Marta; Śmietanka, Krzysztof; Cuvelier-Mizak, Beata. Animal coronaviruses in the light of COVID-19. Journal of Veterinary Research. 2020-08-02, 64 (3): 333–345. doi:10.2478/jvetres-2020-0050.

[pmid30634396-2] Banerjee A, Kulcsar K, Misra V, Frieman M, Mossman K. Bats and Coronaviruses.. Viruses. 2019, 11 (1). PMC 6356540 . PMID 30634396. doi:10.3390/v11010041.

[pmid25787280-3] 3.0 ^3.1 Liu C, Tang J, Ma Y, Liang X, Yang Y, Peng G; et al. Receptor usage and cell entry of porcine epidemic diarrhea coronavirus.. J Virol. 2015, 89 (11): 6121–5. PMC 4442452 . PMID 25787280. doi:10.1128/JVI.00430-15.

[pmid25428871-4] 4.0 ^4.1 Li F. Receptor recognition mechanisms of coronaviruses: a decade of structural studies.. J Virol. 2015, 89 (4): 1954–64. PMC 4338876 . PMID 25428871. doi:10.1128/JVI.02615-14.

[pmid32555182-5] Yu J, Qiao S, Guo R, Wang X. Cryo-EM structures of HKU2 and SADS-CoV spike glycoproteins provide insights into coronavirus evolution.. Nat Commun. 2020, 11 (1): 3070. PMC 7300015 . PMID 32555182. doi:10.1038/s41467-020-16876-4.

[pmid28956766-6] Li Z, Zhao K, Lan Y, Lv X, Hu S, Guan J; et al. Porcine Hemagglutinating Encephalomyelitis Virus Enters Neuro-2a Cells via Clathrin-Mediated Endocytosis in a Rab5-, Cholesterol-, and pH-Dependent Manner.. J Virol. 2017, 91 (23). PMC 5686734 . PMID 28956766. doi:10.1128/JVI.01083-17.

[pmid30873421-7] Mora-Díaz JC, Piñeyro PE, Houston E, Zimmerman J, Giménez-Lirola LG. Porcine Hemagglutinating Encephalomyelitis Virus: A Review.. Front Vet Sci. 2019, 6: 53. PMC 6402421 . PMID 30873421. doi:10.3389/fvets.2019.00053.

[pmid28628449-8] Lorbach JN, Wang L, Nolting JM, Benjamin MG, Killian ML, Zhang Y; et al. Porcine Hemagglutinating Encephalomyelitis Virus and Respiratory Disease in Exhibition Swine, Michigan, USA, 2015.. Emerg Infect Dis. 2017, 23 (7): 1168–1171. PMC 5512476 . PMID 28628449. doi:10.3201/eid2307.170019.

[WooLau2012-9] Woo, P. C. Y.; Lau, S. K. P.; Lam, C. S. F.; Lau, C. C. Y.; Tsang, A. K. L.; Lau, J. H. N.; Bai, R.; Teng, J. L. L.; Tsang, C. C. C.; Wang, M.; Zheng, B.-J.; Chan, K.-H.; Yuen, K.-Y. Discovery of Seven Novel Mammalian and Avian Coronaviruses in the Genus Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of Alphacoronavirus and Betacoronavirus and Avian Coronaviruses as the Gene Source of Gammacoronavirus and Deltacoronavirus. Journal of Virology. 2012, 86 (7): 3995–4008. ISSN 0022-538X. doi:10.1128/JVI.06540-11.

[pmid31961296-10] Boley PA, Alhamo MA, Lossie G, Yadav KK, Vasquez-Lee M, Saif LJ; et al. Porcine Deltacoronavirus Infection and Transmission in Poultry, United States1.. Emerg Infect Dis. 2020, 26 (2): 255–265. PMC 6986833 . PMID 31961296. doi:10.3201/eid2602.190346.

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猪冠状病毒

参考文献

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