Mammalian protein found in Homo sapiens
Natural cytotoxicity triggering receptor 1 is a protein that in humans is encoded by the NCR1 gene .[ 5] [ 6] CD335 (cluster of differentiation , NKP46, NKp46, NK-p46, and LY94 .[ 7]
References
^ a b c ENSG00000277629, ENSG00000273916, ENSG00000275156, ENSG00000277824, ENSG00000277334, ENSG00000278362, ENSG00000275637, ENSG00000274053, ENSG00000275521, ENSG00000275822, ENSG00000277442, ENSG00000189430, ENSG00000284113, ENSG00000273506, ENSG00000276450, ENSG00000278025, ENSG00000288651 GRCh38: Ensembl release 89: ENSG00000273535, ENSG00000277629, ENSG00000273916, ENSG00000275156, ENSG00000277824, ENSG00000277334, ENSG00000278362, ENSG00000275637, ENSG00000274053, ENSG00000275521, ENSG00000275822, ENSG00000277442, ENSG00000189430, ENSG00000284113, ENSG00000273506, ENSG00000276450, ENSG00000278025, ENSG00000288651 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000062524 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Pessino A, Sivori S, Bottino C, Malaspina A, Morelli L, Moretta L, Biassoni R, Moretta A (Sep 1998). "Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity" . J Exp Med . 188 (5): 953– 60. doi :10.1084/jem.188.5.953 . PMC 3207313 PMID 9730896 . ^ "Entrez Gene: NCR1 natural cytotoxicity triggering receptor 1" .^ "NCR1 natural cytotoxicity triggering receptor 1 [Homo sapiens (human)] - Gene - NCBI" .
Further reading
Biassoni R, Cantoni C, Marras D, et al. (2004). "Human natural killer cell receptors: insights into their molecular function and structure" . J. Cell. Mol. Med . 7 (4): 376– 87. doi :10.1111/j.1582-4934.2003.tb00240.x . PMC 6740120 PMID 14754506 . Sivori S, Vitale M, Morelli L, et al. (1997). "p46, a Novel Natural Killer Cell–specific Surface Molecule That Mediates Cell Activation" . J. Exp. Med . 186 (7): 1129– 36. doi :10.1084/jem.186.7.1129 . PMC 2211712 PMID 9314561 . Vitale M, Bottino C, Sivori S, et al. (1998). "NKp44, a Novel Triggering Surface Molecule Specifically Expressed by Activated Natural Killer Cells, Is Involved in Non–Major Histocompatibility Complex–restricted Tumor Cell Lysis" . J. Exp. Med . 187 (12): 2065– 72. doi :10.1084/jem.187.12.2065 . PMC 2212362 PMID 9625766 . Cantoni C, Bottino C, Vitale M, et al. (1999). "NKp44, A Triggering Receptor Involved in Tumor Cell Lysis by Activated Human Natural Killer Cells, Is a Novel Member of the Immunoglobulin Superfamily" . J. Exp. Med . 189 (5): 787– 96. doi :10.1084/jem.189.5.787 . PMC 2192947 PMID 10049942 . Vankayalapati R, Wizel B, Weis SE, et al. (2002). "The NKp46 receptor contributes to NK cell lysis of mononuclear phagocytes infected with an intracellular bacterium" . J. Immunol . 168 (7): 3451– 7. doi :10.4049/jimmunol.168.7.3451 PMID 11907104 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899– 903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Augugliaro R, Parolini S, Castriconi R, et al. (2003). "Selective cross-talk among natural cytotoxicity receptors in human natural killer cells" . Eur. J. Immunol . 33 (5): 1235– 41. doi :10.1002/eji.200323896 PMID 12731048 . S2CID 10724743 . Ponassi M, Cantoni C, Biassoni R, et al. (2003). "Structure of the human NK cell triggering receptor NKp46 ectodomain". Biochem. Biophys. Res. Commun . 309 (2): 317– 23. doi :10.1016/j.bbrc.2003.08.007 . PMID 12951052 . Foster CE, Colonna M, Sun PD (2003). "Crystal structure of the human natural killer (NK) cell activating receptor NKp46 reveals structural relationship to other leukocyte receptor complex immunoreceptors" . J. Biol. Chem . 278 (46): 46081– 6. doi :10.1074/jbc.M308491200 PMID 12960161 . Arnon TI, Achdout H, Lieberman N, et al. (2004). "The mechanisms controlling the recognition of tumor- and virus-infected cells by NKp46" . Blood . 103 (2): 664– 72. doi :10.1182/blood-2003-05-1716 PMID 14504081 . Marcenaro E, Augugliaro R, Falco M, et al. (2004). "CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity" . Eur. J. Immunol . 33 (12): 3367– 76. doi :10.1002/eji.200324425 PMID 14635045 . S2CID 40345630 . Carbone E, Neri P, Mesuraca M, et al. (2005). "HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells" . Blood . 105 (1): 251– 8. doi :10.1182/blood-2004-04-1422 PMID 15328155 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121– 7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Mavoungou E, Bouyou-Akotet MK, Kremsner PG (2005). "Effects of prolactin and cortisol on natural killer (NK) cell surface expression and function of human natural cytotoxicity receptors (NKp46, NKp44 and NKp30)" . Clin. Exp. Immunol . 139 (2): 287– 96. doi :10.1111/j.1365-2249.2004.02686.x . PMC 1809301 PMID 15654827 . Nowbakht P, Ionescu MC, Rohner A, et al. (2005). "Ligands for natural killer cell-activating receptors are expressed upon the maturation of normal myelomonocytic cells but at low levels in acute myeloid leukemias" . Blood . 105 (9): 3615– 22. doi :10.1182/blood-2004-07-2585 PMID 15657183 . Poggi A, Massaro AM, Negrini S, et al. (2005). "Tumor-induced apoptosis of human IL-2-activated NK cells: role of natural cytotoxicity receptors" . J. Immunol . 174 (5): 2653– 60. doi :10.4049/jimmunol.174.5.2653 PMID 15728472 . Zilka A, Landau G, Hershkovitz O, et al. (2006). "Characterization of the heparin/heparan sulfate binding site of the natural cytotoxicity receptor NKp46". Biochemistry . 44 (44): 14477– 85. doi :10.1021/bi051241s . PMID 16262248 . Hermann E, Alonso-Vega C, Berthe A, et al. (2006). "Human congenital infection with Trypanosoma cruzi induces phenotypic and functional modifications of cord blood NK cells" . Pediatr. Res . 60 (1): 38– 43. doi :10.1203/01.pdr.0000220335.05588.ea PMID 16690951 .
External links
1–50 51–100 101–150 151–200 201–250 251–300 301–350
