The community is located on Hashuqua Creek and in 1900 had a population of 125. It was once home to three churches, two stores, a saw mill, and cotton gin.[4]
A post office operated under the name Mashulaville from 1838 to 1960.[5]
In the 1960s, Mennonites settled in Mashulaville after founding a mission to the Choctaw.[6] The Mennonites operate the Mashulaville Dormitory, which is housed in the former Noxubee County Agricultural High School. The dormitory provides housing for mission work and serves as a location for community programs.[7]
The Mashulaville Baptist Church is one of the oldest Baptist church structures in Mississippi.[8]