EA-2192

EA-2192
Names
	Preferred IUPAC name S-{2-[Di(propan-2-yl)amino]ethyl} methylphosphonothioate
	Other names Diisopropylaminoethyl methyl thiolophosphonate
Identifiers
CAS Number	73207-98-4;
3D model (JSmol)	Interactive image;
ChemSpider	46845;
PubChem CID	51760;
UNII	5J7SBT85UY ;
CompTox Dashboard (EPA)	DTXSID00223454 ;
	SMILES CC(C)N(CCSP(=O)(C)O)C(C)C;
Properties
Chemical formula	C9H22NO2PS
Molar mass	239.31 g·mol−1
Appearance	White solid
Solubility in water	Very soluble
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Extremely toxic
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	630 μg/kg (Rat, oral); 18 μg/kg (Rat, iv); 50 μg/kg (Mouse, iv)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

EA-2192 is an extremely toxic degradation product of the VX nerve agent.^[1]^[2] It is a white solid that is very soluble and stable in water.

EA-2192 is an extremely potent acetylcholinesterase inhibitor. It is almost as toxic as VX itself.^[3]

EA-2192 behaves similar to aged Soman as it is the dealkylated form of VX and cannot be reversed with common oxime reactivators.

References

^ Ellison, D. Hank (2007). Handbook of chemical and biological warfare agents (2nd ed.). Boca Raton, Fla.: CRC. ISBN 9780849314346.
^ Hoenig, Steven L. (2007), Compendium of Chemical Warfare Agents, Springer, ISBN 978-0-387-34626-7
^ Munro, NB; Talmage, SS; Griffin, GD; Waters, LC; Watson, AP; King, JF; Hauschild, V (December 1999). "The sources, fate, and toxicity of chemical warfare agent degradation products". Environmental Health Perspectives. 107 (12): 933–74. doi:10.1289/ehp.99107933. PMC 1566810. PMID 10585900.