May 1 – At least six people are killed and 30 others are injured in Illinois after a dust storm causes a crash involving 70 to 90 vehicles on Interstate 55.[4]
July 23 – Six people are killed and 20 others are injured in shootings across Chicago.[9]
July 30 – One person is killed and eight others are critically injured in a mass shooting in the West Side of Chicago.[10]
September 29 – Five people are killed and five more are hospitalized as a semi truck carrying a toxic substance turns over near Teutopolis, causing evacuations.[11]
October 25 – A man is charged with hate crimes after being accused of pepper spraying pro-Palestine protesters that gathered near an Israel solidarity event at a banquet hall in northern Chicago.[13]