环丁基甲酸左炔诺孕酮

环丁基甲酸左炔诺孕酮

臨床資料
其他名稱	HRP-001; HRP001; Levonorgestrel cyclobutyl-carboxylate; Levonorgestrel cyclobutanecarboxylate; Levonorgestrel 17β-cyclobutylcarboxylate; 17α-Ethynyl-18-methyl-19-nortestosterone 17β-cyclobutylcarboxylate; 17α-Ethynyl-18-methylestr-4-en-17β-ol-3-one 17β-cyclobutylcarboxylate; 13-Ethyl-17α-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one cyclobutanecarboxylate
给药途径	肌肉注射
藥物類別（英语：Drug class）	孕激素特别是孕激素酯
识别信息
IUPAC命名法 [(8R,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-3-oxo-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl] cyclobutanecarboxylate
CAS号	86679-36-9
PubChem CID	10092040
ChemSpider	21165289
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID00235759
ECHA InfoCard	100.081.126
化学信息
化学式	C26H34O3
摩尔质量	394.56 g·mol^−1
3D模型（JSmol（英语：JSmol））	交互式图像
SMILES CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)OC(=O)C4CCC4)CCC5=CC(=O)CC[C@H]35
InChI InChI=1S/C26H34O3/c1-3-25-14-12-21-20-11-9-19(27)16-18(20)8-10-22(21)23(25)13-15-26(25,4-2)29-24(28)17-6-5-7-17/h2,16-17,20-23H,3,5-15H2,1H3/t20-,21+,22+,23-,25-,26-/m0/s1 Key:WWGTWFPUIPEHNX-UKNJCJGYSA-N

环丁基甲酸左炔诺孕酮（英語：Levonorgestrel cyclobutylcarboxylate，或称为左炔诺孕酮-17β-环丁基甲酸酯，levonorgestrel 17β-cyclobutylcarboxylate，开发代号：HRP-001）是一种有机化合物，分子式C₂₆H₃₄O₃，属于孕激素酯，从未上市销售。[1][2][3]

参考文献

1. Benagiano G, Merialdi M. Carl Djerassi and the World Health Organisation special programme of research in human reproduction. (PDF). Journal für Reproduktionsmedizin und Endokrinologie-Journal of Reproductive Medicine and Endocrinology. 2011, 8 (1): 10–13. 
2. Garza-Flores J, Hall PE, Perez-Palacios G. Long-acting hormonal contraceptives for women. The Journal of Steroid Biochemistry and Molecular Biology. 1991, 40 (4–6): 697–704. PMID 1958567. S2CID 26021562. doi:10.1016/0960-0760(91)90293-E. 
3. Wu L, Janagam DR, Mandrell TD, Johnson JR, Lowe TL. Long-acting injectable hormonal dosage forms for contraception. Pharmaceutical Research. July 2015, 32 (7): 2180–2191. PMID 25899076. S2CID 12856674. doi:10.1007/s11095-015-1686-2.