The use of medicinal plants in treating diabetes mellitus is increasing in Indonesia. Plenty of plants from different regions may have anti-diabetic effect, including Helminthostachys zeylanica. This plant is commonly used as a traditional medicine to treat inflammation, cough, dysentery, and malaria in Talang Mamak tribe, Indragiri Hulu, Riau, however in China it is used to treat diabetic. Thus, we examined whether the extract of H. zeylanica originated from Riau have potential antidiabetic activity. We assessed the ?-glucosidase inhibitory activity of the extract of H. zeylanica rhizome. The results showed the antidiabetic values of n-hexane, dichloromethane (DCM), ethyl acetate (EtOAc), methanol (MetOH), and ethanol (EtOH) extracts were 380.88 ± 0.09; 190.76 ± 0.22; 61.18 ± 0.59; 47.86 ± 0.06; and 60.78± 0.02, respectively. Acarbose were used as standard with antioxidant values of 19.73± 0.07. It can be concluded that the methanol extract is potential to be proposed as antidiabetic.
| Published by | Universitas Padjadjaran |
| Journal Name | Pharmacology and Clinical Pharmacy Research |
| Contact Phone | - |
| Contact Name | Widya Norma Insani, M.Sc., Apt. |
| Contact Email | Widya Norma Insani, M.Sc., Apt. |
| Location | Kab. sumedang, Jawa barat INDONESIA |
| Website | pcpr| http://jurnal.unpad.ac.id/index.php/pcpr| |
| ISSN | ISSN : 25277332, EISSN : 26140020, DOI : -, |
| Core Subject | Health, |
| Meta Subject | Medicine & Pharmacology, |
| Meta Desc | Pharmacology and Clinical Pharmacy Research (PCPR) is an international, peer-reviewed journal, publishing original research, review, case reports, and commentaries on all aspects of pharmacology and clinical pharmacy. The journal aims to contribute to the scientific committee by publishing the high quality articles. It is published 3 times a year to provide a forum for pharmacologists, pharmacists, and other healthcare professionals to share best practice, encouraging networking, and a more collaborative approach in pharmacology and clinical pharmacy. |
| Penulis | Ridhasya, Fania E. , Teruna, Hilwan Y. , Hendra, Rudi , Almurdani, Muhammad |
| Publisher Article | Universitas Padjadjaran, Indonesia |
| Subtitle Article | Pharmacology and Clinical Pharmacy Research Vol 4, No 3 |
| Scholar Google | http://scholar.google.com/scholar?q=%2Bintitle%3A&… |
| View Article | http://jurnal.unpad.ac.id/pcpr… |
| DOI | https://doi.org/10.15416/pcpr.v4i3.… |
| DOI Number | DOI: 10.15416/pcpr.v4i3.24897 |
| Download Article [1] | http://jurnal.unpad.ac.id/pcpr/article/d… |
| Download Article [2] | http://download.garuda.ristekdikti.go.id… |
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