PIK3R3

Subunidad reguladora gamma de la fosfatidilinositol 3-quinasa

Estructura tridimensional de la proteína PIK3R3.
Estructuras disponibles
PDB

Buscar ortólogos: PDBe, RCSB

 Lista de códigos PDB
2pna
Identificadores
Símbolos PIK3R3 (HGNC: 8981) DKFZp686P05226; FLJ41892; p55-GAMMA
Identificadores
externos
Locus Cr. 1 p34.1
Ortólogos
Especies
Humano Ratón
Entrez
8503
UniProt
Q92569 n/a
RefSeq
(ARNm)
NP_003620 n/a
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La subunidad reguladora gamma de la fosfatidilinositol 3-quinasa (PIK3R3) es una enzima codificada en humanos por el gen PIK3R3.[1]​[2]​

Interacciones

La proteína PIK3R3 ha demostrado ser capaz de interaccionar con:

Referencias

  1. ↑ Dey BR, Furlanetto RW, Nissley SP (mayo de 1998). «Cloning of human p55 gamma, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor». Gene 209 (1-2): 175-83. PMID 9524259. 
  2. ↑ «Entrez Gene: PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)». 
  3. ↑ a b Mothe, I; Delahaye L, Filloux C, Pons S, White M F, Van Obberghen E (Dec. de 1997). «Interaction of wild type and dominant-negative p55PIK regulatory subunit of phosphatidylinositol 3-kinase with insulin-like growth factor-1 signaling proteins». Mol. Endocrinol. (UNITED STATES) 11 (13): 1911-23. ISSN 0888-8809. PMID 9415396. 
  4. ↑ Xia, X; Serrero G (Aug. de 1999). «Multiple forms of p55PIK, a regulatory subunit of phosphoinositide 3-kinase, are generated by alternative initiation of translation». Biochem. J. (ENGLAND). 341 ( Pt 3): 831-7. ISSN 0264-6021. PMID 10417350. 
  5. ↑ Xia, Xianmin; Cheng Aiwu, Akinmade Damilola, Hamburger Anne W (Mar. de 2003). «The N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrest». Mol. Cell. Biol. (United States) 23 (5): 1717-25. ISSN 0270-7306. PMID 12588990.