Zymotic diseaseZymotic disease was a 19th-century medical term for acute infectious diseases,[1] especially "chief fevers and contagious diseases (e.g. typhus and typhoid fevers, smallpox, scarlet fever, measles, erysipelas, cholera, whooping-cough, diphtheria, etc.)".[2] Zyme or microzyme was the name of the organism presumed to be the cause of the disease.
In the late 19th century, Antoine Béchamp proposed that tiny organisms he termed microzymas, and not cells, are the fundamental building block of life. Béchamp claimed these microzymas are present in all things—animal, vegetable, and mineral—whether living or dead. Microzymas coalesce to form blood clots and bacteria. Depending upon the condition of the host, microzymas assume various forms. In a diseased body, the microzymas become pathological bacteria and viruses. In a healthy body, microzymas form healthy cells. When a plant or animal dies, the microzymas live on. His ideas did not gain acceptance.[3] The word zymotic comes from the Greek word ζυμοῦν zumoûn which means "to ferment". It was in British official use from 1839.[4] This term was used extensively in the English Bills of Mortality as a cause of death from 1842. In 1877, Thomas Watson wrote in a Scientific American article "Zymotic Disease" describing contagion as the origin of infectious diseases.[5] Robert Newstead (1859–1947) used this term in a 1908 publication in the Annals of Tropical Medicine and Parasitology, to describe the contribution of house flies (Musca domestica) towards the spread of infectious diseases. However, by the early 1900s, bacteriology "displaced the old fermentation theory",[2] and so the term became obsolete. In her Diagram of the causes of mortality in the army in the East, Florence Nightingale depicts
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