At the age of twelve, she was a regular performer on the television program Nashville on the Road.[9][10][11][12]
Holcombe performed at the Grand Ole Opry[13] and on the Eddie Rabbitt Show.[14] As well as the banjo she also played the fiddle, dobro, steel guitar, and bass.[15]
Holcombe toured throughout the United States, singing and playing the banjo, including The Strip in Las Vegas.[14][16] She performed at Wembley Festival in London, England. She also appeared regularly on the show Nashville Swing, and recorded a television special, Wendy Hooper, US Army that aired on NBC in 1981.[4] She frequently performed duets and comedy sketches with Buck Trent, and the pair were nominated for a Music City Award.[14]
Holcombe died of a congenital heart defect at the age of 23.[17]