User talk:Notpayingthepsychiatrist
HypoxiaHi. Yesterday, I added a paragraph on fetal hypoxia to Causes_of_schizophrenia#Other. You should consider adding some of the information posted at Talk:Causes_of_schizophrenia there, lest it go to waste. Just keep in mind that we have policies against original research, including synthesis of sources to make an original conclusion -- so any new citations will need to make the connection between hypoxia and schizophrenia themselves. --AnotherSolipsist (talk) 19:51, 13 May 2008 (UTC) Thankyou very much for telling me that, thanks for reading the research and I will avoid synthesis of research.
Hi! I added maintenance tags to some material you added to this section. A key difficulty is that you didn't supply any sources for this material. Wikipedia's no original research and verifiability policies prohibit material which cannot be verified by reliable sources and make contributors responsible for supplying appropriate sources. The material you added about certain Bible passages being vague may, for all someone attempting to verify can tell, be your own personal, possibly original opinion. Please supply sources identifying specific commentators who both identify these passages as vague and conclude that this vagueness is a basis for skepticism. The policy explains that unsourced material is subject to deletion. Best, --Shirahadasha (talk) 23:55, 27 July 2008 (UTC)
August 2008Please do not delete content or templates from pages on Wikipedia, as you did to Causes of schizophrenia, without giving a valid reason for the removal in the edit summary. Your content removal does not appear constructive, and has been reverted. Please make use of the sandbox if you'd like to experiment with test edits. Thank you. Elenseel (talk) 17:08, 12 August 2008 (UTC) Hi Notpayingthepsychiatrist, I think it can be assumed that Elensee (understandably) mistook the cuts for vandalism, but that they could be re-done as per the prior talk page discussion. I'd do it myself but it's not clear to me and you know the material better. But I may want to make additional edits/cuts for other material that seems too general, off-topic or original research. The Philip Seeman protein folding section in the neural section could do with simplifying/shortening too, the article is specifically on causes so personally I would say it can go into more detail than the schizophrenia article itself, but it needs to remain user-friendly and each issue given only its due weight/coverage. Cheers EverSince (talk) 16:00, 15 August 2008 (UTC) Hi, Notpayingthepsychiatrist, you left a note on my talk page asking about a revert to your edits on Causes of schizophrenia. Suggest discussing the matter with Elenseel if it hasn't already been taken care of. Best, --Shirahadasha (talk) 04:19, 17 August 2008 (UTC) Hypoxia causes axon guidance deficits
StatsHi Steve, Really when using sources you should generally go with the conclusions as drawn by the authors themselves. Although they say in the main article that they're going to analyse demographic variables including pregnancy complications, they don't seem to conclude anything much about them (but conclude the findings may be due to a wide range of possible genetic and epigenetic causes I think). In any case, probability estimates from statistical significance tests are very specific to the particular test used and the sample size and the study methodology etc, so I would say they can't really be taken out of that context and used to support general statements about links between things. Also, since pregnancy was only one of the factors analyzed in the article/supplement, only highlighting that one in the article seems to give a biased impression. By the way we should probably keep such discussions, that are part of the ongoing development of the content of a particular article, on that article's talk page so that any editors can see what's happening and perhaps comment... using user pages for more indirectly related issues or things more specific to each of us. EverSince (talk) 18:52, 31 August 2008 (UTC) Hi again, I was wondering if by any chance you have online access to the full text of PMID 15062627? EverSince (talk) 18:58, 30 September 2008 (UTC)
File copyright problem with File:Graph2.jpgThank you for uploading File:Graph2.jpg. However, it currently is missing information on its copyright status. Wikipedia takes copyright very seriously. It may be deleted soon, unless we can determine the license and the source of the file. If you know this information, then you can add a copyright tag to the image description page. If you have uploaded other files, consider checking that you have specified their license and tagged them, too. You can find a list of files you have uploaded by following this link. If you have any questions, please feel free to ask them at the media copyright questions page. Thanks again for your cooperation. — neuro(talk)(review) 10:39, 6 April 2009 (UTC) Your messageHi, got your message. Answered at my talk. --Tryptofish (talk) 21:24, 29 July 2009 (UTC) delusionsYou said: Hi, please check 'specific delusions' under 'delusion' it is a December copy and is more readable, it's not original research as under 'Delusion' X is a type of Y. Notpayingthepsychiatrist (talk) 19:13, 29 July 2009 (UTC) Sorry, I am a bit tired today, which bit are you referring to here in particular? I didn't follow "december copy"...cheers, Casliber (talk · contribs) 10:29, 30 July 2009 (UTC)
Copyright questionsPlease sent all correspondence to the Wikimedia volunteers mailing list at permissions-enwikimedia.org. Releasing personally identifiable information about others without their express consent, as was done in the e-mails, is not allowed for editor protection, so I removed the conversation. Thank you for understanding. -- Avi (talk) 16:54, 30 September 2009 (UTC) Your messageHi, got your message. Answered at my talk. --Tryptofish (talk) 20:03, 10 February 2010 (UTC) IncubationHi Innab, I am interested in your post on Causes of Schizophrenia about addiction. This website, for example says a sexy image, for example, will elicit a dopamine spike, but not of long duration. http://ieet.org/index.php/IEET/more/kuszewski20100828 "So what are the take-home points? Imagery and suggestion that is blatant and forceful may get a big spike in dopamine, but it will be short-lived. This isn’t giving you enough time to feel the attachment effects of oxytocin to the fullest extent possible. The element of mystery is a trigger for dopamine — in figuring out that mystery, we are intrigued, drawn in, motivated to examine it closer. If a stimulus is more abstract and leaves a little to the imagination, you will spend more time on it, thus extending every pleasurable neurochemical process, giving you a prolonged neurological orgasm. " d2 receptors, in order to turn to d2high, need incubation in dopamine. Have you got a quote which says this can be achieved by thought only? Steve Notpayingthepsychiatrist (talk) 09:28, 7 September 2010 (UTC) Infact this article actually says sexual arousal is inhibited by stimulation of the schizophrenia receptor: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T0P-3TVNH8Y-N&_user=10&_coverDate=09%2F30%2F1997&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_searchStrId=1453147183&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=106e61b723100a0260a2826c424d178f&searchtype=a Notpayingthepsychiatrist (talk) 10:16, 7 September 2010 (UTC)
++++++++++++++ Original Block in Schizophrenia article ++++++++++++++++++ Increased dopamine and serotonin activity in the mesolimbic pathway of the brain is consistently found in individuals with Schizophrenia and OCD by number of independent studies.[1][2][3][4] Dopamine is released (particularly in areas such as the nucleus accumbens and prefrontal cortex) by rewarding experiences such as food, sex, drugs (like amphetamines), neutral stimuli that become associated with them. Researches has found that even thinking about reward like sex, drugs, alcohol, food, can increase the dopamine levels.[5][6][7] This explains placebo effect, for example.[8] Dopamine and serotonin are commonly associated with the reward system of the brain, providing feelings of enjoyment and reinforcement to motivate a person proactively to perform certain activities. However, some patients are abusing the "repetitive thoughts" reward system, invoking rewarding memories and thoughts again and again to naturally produce the "feel-good" neurotransmitters in their brain, losing self-control.[4] This is similar to drug addiction: nearly all drugs, directly or indirectly, target the brain’s reward system by flooding the circuit with dopamine.[9][10] As a person continues to overstimulation of the “reward circuit”, the brain adapts to the overwhelming surges in dopamine by producing less of the neurotransmitter or by reducing the number of receptors in the reward circuit.[10] As a result, chemical’s impact on the reward circuit is lessened, reducing the abuser’s ability to enjoy the things that previously brought pleasure.[9][4] The decrease in neurotransmitters flow compels those addicted to dopamine to increasingly think rewarding thoughts in order to attempt to bring the neurotransmitter level back to normal - an effect known as tolerance.[9][4] This can explain why many of the schizophrenia and OCD patients have increased levels of dopamine. Development of the tolerance can eventually lead to profound changes in neurons and brain circuits, with the potential to severely compromise the long-term health of the brain.[11] Modern antipsychotics are designed to block dopamine function. However, excessive blocking can also cause relapses in depression, and can increase addictive behaviors.[12] Cognitive behavioral therapy (CBT) done by mental health professional can also be effectively used to control obsessive thoughts and compulsion acts, improves self-esteem, deals with depression factors and explains patients negative long-term consequences of dopamine addiction.[13][14] Comparing the neurons to plumber pipes, I see 4 ways to increase the dopamine flow into the receiving neuron of the synapse (see the picture):
The counterpart of the pleasure principle, according to Sigmund Freud is the reality principle, which defers gratification when necessary. When level of dopamine is too high brain cannot function properly, so to block flow of neurotransmitters we can:
I would be very grateful for any of your help with the article. Innab (talk) 19:26, 21 September 2010 (UTC) Hi Innab, thanks for replying. When you resubmit the text just reference this statement: "some patients [citation needed] are abusing the repetitive thoughts reward system,". Steve Notpayingthepsychiatrist (talk) 20:15, 23 September 2010 (UTC)
Hi Innab, I had a quick look at the Schizophrenia Bulletin page, but when I searched it I couldn't find anything mentioning 'obsession'. Here is a quote from a web page, the page would not have enough authority on its own, but it mentions a study from Columbia university - perhaps this study mentions schizophrenia?: " A Columbia University study found that sexually active teens use more drugs. One might think social factors alone lead to this correlation between drugs and sex, but when scientists studied hamsters, they found that sexually-active hamsters were much more susceptible to amphetamine addiction than their virgin counterparts." http://www.reuniting.info/science/sex_in_the_brain. Good luck. Notpayingthepsychiatrist (talk) 13:30, 1 October 2010 (UTC)
References
With best wishes
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