For UEFA Euro 2012, Ukraine qualified automatically as one of the host countries, marking their début at the major European football tournament. In their opening game against Sweden, Ukraine won 2–1 in Kyiv. Despite the team's efforts, the co-hosts were eliminated after a 0–2 loss to France and a 0–1 loss to England, both in Donetsk. Euro 2012 was the second international tournament at which Ukraine appeared, following the 2006 FIFA World Cup.
For Euro 2016, Ukraine qualified via the play-offs, defeating Slovenia. At the finals in France, they lost all three matches without scoring a goal.
Ukraine qualified for Euro 2020 by finishing top of their qualifying group, and reached the quarter-finals of the tournament for the first time after defeating Sweden 2–1 in the round of 16 after extra time, before being eliminated by England.
Ukraine qualified for Euro 2024 via the play-offs, following a 2–1 victory against Iceland. Despite finishing the group stage with four points, Ukraine still finished bottom due to their inferior goal difference, and were eliminated.