Sterol carrier protein

Sterol carrier protein 2
Identifiers
Symbol	SCP2
Pfam	PF02036
InterPro	IPR003033
PROSITE	PDOC00092
SCOP2	1qnd / SCOPe / SUPFAM
OPM superfamily	135
OPM protein	2cx7
Available protein structures: Pfam   structures / ECOD   PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Sterol carrier proteins (also known as nonspecific lipid transfer proteins) is a family of proteins that transfer steroids and probably also phospholipids and gangliosides between cellular membranes.

These proteins are different from plant nonspecific lipid transfer proteins but structurally similar to small proteins of unknown function from Thermus thermophilus.

This domain is involved in binding sterols. The human sterol carrier protein 2 (SCP2) is a basic protein that is believed to participate in the intracellular transport of cholesterol and various other lipids.[1]

Human proteins containing this domain

HSD17B4; HSDL2; SCP2; STOML1;

See also

• Steroidogenic acute regulatory protein and START domain

References

1. Johansson J, Wuthrich K, Szyperski T, Scheek S, Assmann G, Seedorf U (1993). "NMR determination of the secondary structure and the three-dimensional polypeptide backbone fold of the human sterol carrier protein 2". FEBS Lett. 335 (1): 18–26. doi:10.1016/0014-5793(93)80431-S. PMID 8243660. S2CID 9969358.

External links

• Sterol carrier proteins in SCOP
• SCP-2 sterol transfer family in Pfam
• UMich Orientation of Proteins in Membranes families/superfamily-144
• sterol+carrier+proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the public domain Pfam and InterPro: IPR003033