Serotonin–norepinephrine releasing agentA serotonin–norepinephrine releasing agent (SNRA) is a type of drug which induces the release of serotonin and norepinephrine (and epinephrine) in the body and/or brain. Only a few SNRAs are known, examples of which include norfenfluramine, (R)-MDMA, MBDB, and MDAI. Fenfluramine/phentermine (Fen-Phen), a combination formulation of fenfluramine, a serotonin releasing agent, and phentermine, a norepinephrine releasing agent, is a functional SNRA that was formerly used as an appetite suppressant for the treatment of obesity. A closely related type of drug is a serotonin–norepinephrine reuptake inhibitor (SNRI). See also
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