While in the first grade, his parents signed Sergey to the sambo/judo. In the military camp, he got jaundice, passed the full course of treatment in the local hospital, upon arrival in his native town, he was recovering for half a year, with his motor activity being kept to a minimum and having a strict diet. Then he began practicing karate at the age of 15, which was supposed to be a very late age for this kind of martial arts, but a year later he was Champion of Moscow and Russia in Ashihara Karate. Then his family moved to Odintsovo, where his father, being a military man, got an apartment. Hee joined the martial arts because he couldn't find a karate coach.[2][3][4]
By the adolescence keenness for sports went down. Having recovered, he went to the hand-to-hand fighting section at the age of 14-15, where he took karate, his trainer - Alexander Ivanovich Zhokin. Since the age of 16 Khandozhko became more than one champion of Moscow and Russia in his weight, but did not have a corresponding belt.[4]
In October 2010 became a winner at the World Championship in all-round combat. In 2011 took the 1st place at the IX Open Championship of the Kryukovo Municipality in the hand-to-hand fighting (punkration version) in the category up to 80 kg., 2nd place in the category up to 80 kg at the Cup in the hand-to-hand fighting, 2nd place at the Championship of Russia in the universal fighting in the category up to 80 kg., 1st place in the championship in hand-to-hand fighting "Russian Bogatyr". In June - the winner of amateur championship on MMA in the category up to 85 kg. July - 1st place in the category up to 80 kg. on the European Championship on Universal Fighting; October - 1st place on the World Championship on Universal Fighting. During the same period became bronze medalist of the Moscow Open MMA Championship among men over 18 in the category up to 80 kg.[4]
Since 2018, he has been acting director of the State Budgetary Institution of the KK of the sports school "Regional Martial Arts Center".[4]
Mixed martial arts career
Early career
Making his professional MMA debut in 2011 against Dmitry Lapatin, winning by technical knockout in the first round. Studying at the university of the system of the Ministry of Internal Affairs of Russia and not having enough time for full-fledged training, they studied with a classmate V. Myasnikov in the kitchen of the hostel. He suffered his first defeat from Eduard Vartanyan in May 2013 at the Legend tournament, where Alexander Emelianenko and Bob Sapp met in the main battle.[5]
Khandozhko compiled a 25–5–1 record fighting on the Russian regional scene, fighting most notably with Absolute Championship Berkut, where he faced the likes of future ACA Welterweight champ and fellow UFC fighter Albert Duraev, losing by the way of unanimous decision, but also the likes of Ben Alloway, who he lost to via rear-naked choke in the third round.[5][6]
In the bout right before signing with the UFC, Khandozhko faced Adriano Rodrigues at S-70: Plotforma Cup 2018, where he won the bout via body kick KO in the second round.[7]
Ultimate Fighting Championship
Khandozhko was expected to make his UFC debut against Bartosz Fabiński on June 1, 2019, at UFC Fight Night: Gustafsson vs. Smith,[8] but Fabiński pulled out due to injury and was replaced by Rostem Akman.[9] Sergey won the bout via unanimous decision.[10]