Rikenellaceae

Rikenellaceae
Scientific classification
Domain:	Bacteria
Phylum:	Bacteroidota
Class:	Bacteroidia
Order:	Bacteroidales
Family:	Rikenellaceae Krieg et al. 2012[1]
Genera[2]
Alistipes Rautio et al. 2003 Anaerocella Abe et al. 2013 Gallalistipes Zenner et al. 2021 Mucinivorans Nelson et al. 2015 Rikenella Collins et al. 1985

Rikenellaceae is a family of Gram-negative bacteria described by Noel R. Krieg in 2015. It contains nine genera, five of which are validly published by the International Code of Nomenclature of Prokaryotes.[2] Bacteria with 16S ribosomal RNA highly similar to the Rikenella genus, as compared to the larger taxonomic order Bacteroidales, are classified in this family.[1]

This family consists of non-motile, rod-shaped bacteria that are tolerant of bile. Most Rikenellaceae species have been identified in the gastrointestinal tract microbiomes of various animals.[3]

Bacteria of this taxonomic family are elevated in the gut microbiomes of mice that are leptin-resistant obese and diabetic.[4] However, Rikenellaceae bacteria are depleted in the gut microbiomes of obese American adults, leading to reduced synthesis of butyrate and disrupted metabolism.[5]

Gut microbiomes with elevated levels of Rikenellaceae bacteria are associated with lupus and Alzheimer's disease in mice and colorectal cancer in humans.[6][7][8]

References

1. Krieg, Noel R. (14 September 2015). "Rikenellaceae fam. nov". Bergey's Manual of Systematics of Archaea and Bacteria: 1–2. doi:10.1002/9781118960608.fbm00062. ISBN 9781118960608.
2. Parte, Aidan C.; Carbasse, Joaquim Sardà; Meier-Kolthoff, Jan P.; Reimer, Lorenz C.; Göker, Markus (23 July 2020). "Family Rikenellaceae". List of Prokaryotic names with Standing in Nomenclature. Retrieved 8 April 2023.
3. Graf, Joerg (2014). "The Family Rikenellaceae". In Rosenberg, Eugene; DeLong, Edward F.; Lory, Stephen; Stackebrandt, Erko; Thompson, Fabiano (eds.). The Prokaryotes (4th ed.). Springer Berlin. pp. 857–859. doi:10.1007/978-3-642-38954-2_134. ISBN 978-3-642-38953-5.
4. Cani, Patrice D. (24 April 2013). "Gut Microbiota and Obesity: Lessons from the Microbiome". Briefings in Functional Genomics. 12 (4): 381–387. doi:10.1093/bfgp/elt014. PMID 23616309 – via Oxford Academic.
5. Peters, Brandilyn A.; Shapiro, Jean A.; Church, Timothy R.; Miller, George; Trinh-Shevrin, Chau; Yuen, Elizabeth; Friedlander, Charles; Hayes, Richard B.; Ahn, Jiyoung (2018-06-27). "A taxonomic signature of obesity in a large study of American adults". Scientific Reports. 8 (1): 9749. doi:10.1038/s41598-018-28126-1. ISSN 2045-2322. PMC 6021409. PMID 29950689.
6. Wang, Hui; Wang, Gangduo; Banerjee, Nivedita; Liang, Yuejin; Du, Xiaotang; Boor, Paul J.; Hoffman, Kristi L.; Khan, M. Firoze (12 April 2021). "Aberrant Gut Microbiome Contributes to Intestinal Oxidative Stress, Barrier Dysfunction, Inflammation and Systemic Autoimmune Responses in MRL/lpr Mice". Frontiers in Immunology. 12: 651191. doi:10.3389/fimmu.2021.651191. ISSN 1664-3224. PMC 8071869. PMID 33912174.
7. Bello-Medina, Paola C.; Corona-Cervantes, Karina; Zavala Torres, Norma Gabriela; González, Antonio; Pérez-Morales, Marcel; González-Franco, Diego A.; Gómez, Astrid; García-Mena, Jaime; Díaz-Cintra, Sofía; Pacheco-López, Gustavo (26 July 2022). "Chronic-Antibiotics Induced Gut Microbiota Dysbiosis Rescues Memory Impairment and Reduces ß-Amyloid Aggregation in a Preclinical Alzheimer's Disease Model". International Journal of Molecular Sciences. 23 (15): 8209. doi:10.3390/ijms23158209. ISSN 1422-0067. PMC 9331718. PMID 35897785.
8. Hoang, Tung; Kim, Min Jung; Park, Ji Won; Jeong, Seung-Yong; Lee, Jeeyoo; Shin, Aesun (14 June 2022). "Nutrition-Wide Association Study of Microbiome Diversity and Composition in Colorectal Cancer Patients". BMC Cancer. 22 (1): 656. doi:10.1186/s12885-022-09735-6. ISSN 1471-2407. PMC 9199192. PMID 35701733.