Philip Seeman

Philip Seeman
Born(1934-02-08)8 February 1934
Winnipeg, Manitoba, Canada
Died9 January 2021(2021-01-09) (aged 86)
Toronto, Ontario, Canada
AwardsOrder of Canada

Philip Seeman, OC FRSC (8 February 1934 – 9 January 2021) was a Canadian schizophrenia researcher and neuropharmacologist, known for his research on dopamine receptors.[1]

Career

Born in Winnipeg, Manitoba, Seeman was raised in Montreal. He received a Bachelor of Science degree, honours physics & physiology (1955), a Master of Science degree, physiology of transport & secretion (1956), and a Doctor of Medicine (1960) from McGill University. In 1966, he received a Ph.D. in life sciences from Rockefeller University under the supervision of George Emil Palade.[2]

In 1967, Seeman became an assistant professor in the Department of Pharmacology at the University of Toronto. In 1970, he was appointed a professor.

In 1974, having spent years in search of the binding site of antipsychotic medication, he discovered the dopamine D2 receptor, the basis for the dopamine hypothesis of schizophrenia.[3][4] His discoveries also helped advance research on other diseases involving dopamine, such as Parkinson's disease and Huntington's disease.[2]

In 2001, he was made an Officer of the Order of Canada "for his research on dopamine receptors and their involvement in diseases such as schizophrenia, Parkinson's and Huntington's".[5]

In 1985, he was made a Fellow of the Royal Society of Canada.[6]

He was married to Dr. Mary V. Seeman.[7]

Notes

  1. ^ "Philip SEEMAN". The Globe and Mail. Retrieved 19 January 2021.
  2. ^ a b Peters, Diane (27 January 2021). "Researcher Philip Seeman shed new light on biology of schizophrenia". The Globe and Mail. Retrieved 15 August 2024.
  3. ^ P. Seeman, M. Chau-Wong, J. Tedesco & K. Wong (November 1975). "Brain receptors for antipsychotic drugs and dopamine: direct binding assays". Proceedings of the National Academy of Sciences of the United States of America. 72 (11): 4376–4370. Bibcode:1975PNAS...72.4376S. doi:10.1073/pnas.72.11.4376. PMC 388724. PMID 1060115.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. ^ "People". CMAJ. 151 (8): 1186–1187. 1994. PMC 1337253.
  5. ^ Order of Canada citation
  6. ^ "Science & Medicine - Science & Medicine". www.sciandmed.com. Archived from the original on 2011-07-16.
  7. ^ "Most Wikipedia profiles are about men – these women in Australia are hoping to change that". SBS News. Retrieved 27 July 2019.

References