In 2003, Aycox played Minxie Hayes, a psychic cheerleader, in Jeepers Creepers 2.[2][3] It was the sequel to the 2001 horror film Jeepers Creepers. From July to October 2005, Aycox portrayed Private Brenda "Mrs. B" Mitchell on Over There.[4] The series followed a unit of the United States Army's 3rd Infantry Division on its first tour of duty in occupied Iraq and chronicled the war's effects on the soldiers' families in the United States.
In 2006, Aycox guest starred in Criminal Minds as Amber Canardo, a sociopathic serial killer, in the episode "The Perfect Storm". That same year, she portrayed Meg Masters, a recurring antagonist, in the first season of the WB (now CW) series Supernatural. Executive producer Kim Manners had previously worked with Aycox in an episode of Over There that he directed, and hand-selected her for the role of Meg.[5]
I think that when you bring a woman on that's going to be a powerful character, there's definitely going to be some sexuality put into the character. I added a lot of it on my own, but it was definitely in the script as well.
Aycox on developing Meg for Supernatural, Supernatural: The Official Companion Season 1, p. 140
In July 2009, Aycox began to portray the character Jaimie Allen (an undercover LAPD police officer) in the TNT action/drama series Dark Blue.[8] It ended its run-on September 15, 2010.[9] Her final acting role was in the 2014 film Dead on Campus.[2][3]
In 2015, Aycox released her debut EP, Red Velvet Room, which contained five songs of her own original music.[1]
Personal life and death
In a March 2021 Instagram post, Aycox revealed that she had been diagnosed with leukemia.[4][10] She died from the disease on November 16, 2022, at the age of 47.[11][12]
