At the southeastern end of Neo Souli, on the "Agrianista" hill, has been found an ancient settlement, with continuous habitation from prehistoric to modern years.[2]
In Roman times the settlement belonged to the territory ("chora") of the city of Sirra (modern Serres), from which it was administratively dependent.[3] South of Neo Souli the ancient necropolis was extended, where various archaeological findings (vases, reliefs, coins etc.) were found, as well as Greek inscriptions of the Roman imperial period.[4]
^[1]Archived 2017-04-24 at the Wayback Machine D. C. Samsaris, Historical Geography of Eastern Macedonia during the Antiquity (in Greek), Thessaloniki 1976 (Society for Macedonian Studies), p. 175-176. ISBN960-7265-16-5
^[2] D. C. Samsaris, A History of Serres (in the Ancient and Roman Times) (in Greek), Thessaloniki 1999, p. 162-163 (Website of Municipality of Serres)