Spector was appointed as a Guggenheim curator in 1989.[4]
Spector was adjunct curator of the 1997 Venice Biennale and a co-curator of the first Berlin Biennale in 1998.[5] At the Deutsche Guggenheim, Berlin, she has overseen commissions by Andreas Slominski (1999), Hiroshi Sugimoto (2000), Lawrence Weiner (2000), and Gabriel Orozco (2012), as well as organized the exhibitions Douglas Gordon’s The Vanity of Allegory (2005) and All in the Present Must be Transformed: Matthew Barney and Joseph Beuys (2006).[6]
Nancy Spector was one of the curators of Monument to Now, an exhibition of the Dakis Joannou Collection, which premiered in Athens in 2004 as an official part of the Olympics program.[6]
In 2019, the Guggenheim hired Chaédria LaBouvier to present her exhibition "Basquiat's Defacement: The Untold Story."[8] At the conclusion of the show, LaBouvier accused Spector and the larger institution of creating "the most racist professional experience of my life" and criticized her on social media.[9][10]
In 2020, the Guggenheim hired an external firm to investigate her claims. It ultimately found "no evidence that Ms. LaBouvier was subject to adverse treatment on the basis of her race." However, while the investigation was under way, museum employees submitted a public letter to the board, calling for them to "replace those members of the executive cabinet who have repeatedly proven that they are not committed to decisive, anti-racist action and do not act in good faith with BIPOC leaders."[11]
In October 2020, after the investigation's conclusion, Spector parted ways with the museum.[12][13] An investigative article in The Atlantic, exploring the circumstances of her departure, revealed that she was scapegoated by the museum.[14] Reflecting on the situation in 2023, the International Committee for Museums and Collections of Modern Art (CiMAM) criticized the museum, stating that Spector was "a notable museum professional with a strong track record of representing and enhancing diversity."[15]
Spector, Nancy, Against the Grain: Contemporary Art at the Guggenheim. in Art of this Century: The Guggenheim Museum and Its Collection. New York: Guggenheim Museum, 1993.
Spector, Nancy, “Rauschenberg and Performance, 1963-67: A ‘Poetry of Infinite Possibilities,’” in Robert Rauschenberg: A Retrospective. New York: Guggenheim Museum, 1997.
Spector, Nancy, “Roni Horn: Picturing Place in Roni Horn: Events of Relation. Paris: Musée d’Art Moderne de la Ville de Paris, 1999.
Spector, Nancy, “a.k.a.,” Douglas Gordon. Cambridge, Mass. and Los Angeles: MIT Press and Museum of Contemporary Art, 2001.
Barney, Matthew, Nancy Spector, and Neville Wakefield. Matthew Barney: The Cremaster Cycle. New York: Guggenheim Museum, 2002.
Dennison, Lisa, and Nancy Spector. Singular Forms (sometimes Repeated): Art from 1951 to the Present. [exhibition] Guggenheim Museum. New York: Guggenheim Museum Publications, 2004.
Spector, Nancy. All in the future must be transformed: Matthew Barney and Joseph Beuys. New York: Guggenheim Museum, 2006
Spector, Nancy, and Richard Prince. Richard Prince. New York: Guggenheim Museum, 2007.
Spector, Nancy. Theanyspacewhatever. New York: Guggenheim Museum, 2008.
Spector, Nancy, “Seven Easy Pieces,” Marina Abramović: The Artist is Present. New York: The Museum of Modern Art, 2010.
Spector, Nancy, Maurizio Cattelan, and Nancy Spector. Maurizio Cattelan: All. New York, NY: Guggenheim Museum Publications, 2011, revised and reprinted in 2016.
Spector, Nancy, Gabriel Orozco: Asterisms. New York: Guggenheim Museum, 2012.
Spector, Nancy, ed. Peter Fischli and David Weiss: How to Work Better. New York: Guggenheim Museum, 2015.
Spector, Nancy,“Resentment Demands a Story: Passage dangereux” in Louise Bourgeois: Structures of Existence. Munich: Haus der Kunst, 2015