Yiadom was enstooled as the Asantehemaa with the stool name Nana Konadu Yiadom III,[6] after succeeding her mother and predecessor Nana Afia Kobi Serwaa Ampem II who died on 15 November 2016 in her sleep, aged 109. Before her death, her mother reigned as the Asantehemaa (Queen mother) for 39 years.[7][8][9]
Yiadom was enstooled as the Asantehemaa on 6 February 2017 and was publicly outdoored as by Otumfuo Nana Osei Tutu II on 6 May 2017, which also marked Otumfuo's 67th birthday at a ceremony at the Manhyia Palace in Kumasi.[10][11][12] At the time 2017 when she ascended the stool she was 83 years old.[13]
On 6 February 2022, a thanksgiving ceremony and a durbar were held at the Manhyia Palace in commemoration of her 5th anniversary since ascending the Asantehemaa stool.[14]