NOVA2

NOVA2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1DTJ, 1EC6
Identifiers
Aliases	NOVA2, ANOVA, NOVA3, NOVA alternative splicing regulator 2, NEDASB, NOVA-2
External IDs	OMIM: 601991; MGI: 104296; HomoloGene: 134398; GeneCards: NOVA2; OMA:NOVA2 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.32 Start 45,933,734 bp[1] End 45,974,044 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 A3 Start 18,659,813 bp[2] End 18,699,244 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence tendon of biceps brachii entorhinal cortex postcentral gyrus prefrontal cortex superior frontal gyrus right frontal lobe nucleus accumbens internal globus pallidus Brodmann area 10 Top expressed in Rostral migratory stream lumbar subsegment of spinal cord ganglionic eminence visual cortex dentate gyrus of hippocampal formation granule cell primary visual cortex superior frontal gyrus nucleus of stria terminalis medial ganglionic eminence central gray substance of midbrain More reference expression data BioGPS n/a
Gene ontology Molecular function nucleic acid binding RNA binding Cellular component nucleus Biological process mRNA splicing, via spliceosome regulation of RNA metabolic process negative regulation of cold-induced thermogenesis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4858 384569 Ensembl ENSG00000104967 ENSMUSG00000030411 UniProt Q9UNW9 A0A1W2P872 RefSeq (mRNA) NM_002516 NM_001029877 RefSeq (protein) NP_002507 NP_001025048 Location (UCSC) Chr 19: 45.93 – 45.97 Mb Chr 7: 18.66 – 18.7 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

NOVA alternative splicing regulator 2 is a protein that in humans is encoded by the NOVA2 gene. [5]

References

1. GRCh38: Ensembl release 89: ENSG00000104967 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030411 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: NOVA alternative splicing regulator 2". Retrieved 2018-07-23.

Further reading

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human RNA-binding protein Nova-2