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Michaelis–Gutmann bodies Michaelis–Gutmann bodies (M-G bodies) are concentrically layered basophilic inclusions found in Hansemann cells in the urinary tract. These are 2 to 10 μm in diameter, and are thought to represent remnants of phagosomes mineralized by iron and calcium deposits.[citation needed] M-G bodies are a pathognomonic feature of malakoplakia, an inflammatory condition that affects the genitourinary tract. They were initially discovered in 1902 by Leonor Michaelis and Carl Gutmann.[citation needed] Michaelis-Gutmann bodies stain positive for von kossa (calcium), Prussian Blue (iron), and PAS diastase stain. References |
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