Lactobacillus iners

Lactobacillus iners
Scientific classification
Domain:	Bacteria
Phylum:	Bacillota
Class:	Bacilli
Order:	Lactobacillales
Family:	Lactobacillaceae
Genus:	Lactobacillus
Species:	L. iners
Binomial name
Lactobacillus iners Falsen et al. 1999
Type strain
CCUG 28746T

Lactobacillus iners is a species in the genus Lactobacillus. It is a Gram-positive, catalase-negative, facultatively anaerobic rod-shaped bacterium.[1]

Lactobacillus iners is a normal inhabitant of the lower reproductive tract in healthy women, along with Lactobacillus crispatus, Lactobacillus jensenii, and Lactobacillus gasseri.[2]

Genome

The genomes of at least 15 strains have been sequenced and encode between 1,152 and 1,506 proteins. Thus, this species has one of the smallest Lactobacillus genomes compared to other species, such as L. crispatus, which typically encodes more than twice as many proteins.[3]

References

1. Falsen, E.; Pascual, C.; Sjoden, B.; Ohlen, M.; Collins, M. D. (1999). "Phenotypic and phylogenetic characterization of a novel Lactobacillus species from human sources: description of Lactobacillus iners sp. nov". International Journal of Systematic Bacteriology. 49 (1): 217–221. doi:10.1099/00207713-49-1-217. ISSN 0020-7713. PMID 10028266.
2. Ravel, J; Gajer, P; Abdo, Z; Schneider, GM; Koenig, SS; McCulle, SL; Karlebach, S; Gorle, R; Russell, J; Tacket, CO; Brotman, RM; Davis, CC; Ault, K; Peralta, L; Forney, LJ (15 March 2011). "Vaginal microbiome of reproductive-age women". Proceedings of the National Academy of Sciences of the United States of America. 108 Suppl 1 (Suppl 1): 4680–7. doi:10.1073/pnas.1002611107. PMC 3063603. PMID 20534435.
3. France, Michael T.; Mendes-Soares, Helena; Forney, Larry J. (2016-12-15). "Genomic Comparisons of Lactobacillus crispatus and Lactobacillus iners Reveal Potential Ecological Drivers of Community Composition in the Vagina". Applied and Environmental Microbiology. 82 (24): 7063–7073. doi:10.1128/AEM.02385-16. ISSN 0099-2240. PMC 5118917. PMID 27694231.

Further reading

• Jakobsson, T.; Forsum, U. (2007). "Lactobacillus iners: a Marker of Changes in the Vaginal Flora?". Journal of Clinical Microbiology. 45 (9): 3145. doi:10.1128/JCM.00558-07. ISSN 0095-1137. PMC 2045263. PMID 17652481.
• Rampersaud R, Planet PJ, Randis TM, Kulkarni R, Aguilar JL, Lehrer RI, et al. (2011). "Inerolysin, a cholesterol-dependent cytolysin produced by Lactobacillus iners". J Bacteriol. 193 (5): 1034–41. doi:10.1128/JB.00694-10. PMC 3067590. PMID 21169489.
• Macklaim, Jean M., et al. "At the crossroads of vaginal health and disease, the genome sequence of Lactobacillus iners AB-1." Proceedings of the National Academy of Sciences 108.Supplement 1 (2011): 4688–4695.
• Alqumber, Mohammed A., et al. "A species-specific PCR for Lactobacillus iners demonstrates a relative specificity of this species for vaginal colonization."Microbial Ecology in Health and Disease 20.3 (2008): 135-139.

External links

• "Lactobacillus iners". The Encyclopedia of Life.
• LPSN
• Type strain of Lactobacillus iners at BacDive - the Bacterial Diversity Metadatabase