In 2008, he was recruited by the University of Liverpool to lead a lab studying genomic approaches to aging. In 2022, he was recruited by the University of Birmingham to be Chair of Molecular Biogerontology, and he currently leads the Genomics of Aging and Rejuvenation Lab there.[2]
He helps maintain several databases on aging - among them - GenAge, AnAge, DrugAge,[3] CellAge, GenDR, the Digital Aging Atlas,[4] and Who's Who in Gerontology. His research group helped sequence the transcriptome of the long-lived bowhead whale. He also helps advise the Lifeboat Foundation.
Among his many longevity-related scientific research projects, Magalhães has sequenced and analyzed the genome of the bowhead whale.[5] And he has also contributed to analysis of the genome of the naked mole rat.[6] Both of these mammals are exceptionally long-lived and exceptionally cancer-resistant.