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Idiopathic granulomatous hepatitis
Idiopathic granulomatous hepatitis is a rare medical condition characterized by granulomas in the liver, recurrent fever, myalgia, and fatigue. The condition is not a true hepatitis, and some experts believe it is a variant of sarcoidosis.[1][2] Signs and symptomsIdiopathic granulomatous hepatitis is marked by granuloma in the liver and recurrent fevers.[3] Fatigue and weight loss are other common symptoms.[4] CausesGranulomas in the liver often correspond to a systemic illness that the patient had previously been diagnosed with. Liver granulomas, however, could be a symptom of an unidentified systemic illness or they might not have a discernible underlying cause.[3] DiagnosisEstablishing the diagnosis can be difficult because it needs to rule out other conditions that can cause hepatic granulomas, like lymphoma, sarcoidosis, drug allergies, and infections by fungi or mycobacteria.[3] TreatmentIdiopathic granulomatous hepatitis is treated with methotrexate along with additional immunosuppressive medications such as vinblastine, cyclophosphamide, and chlorambucil.[4] See alsoReferences
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