Hydrangeic acid

Hydrangeic acid
Chemical structure of hydrangeic acid
Names
Preferred IUPAC name
2-Hydroxy-6-[(E)-2-(4-hydroxyphenyl)ethen-1-yl]benzoic acid
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C15H12O4/c16-12-8-5-10(6-9-12)4-7-11-2-1-3-13(17)14(11)15(18)19/h1-9,16-17H,(H,18,19)/b7-4+
    Key: UWXXIBUTKVUHTR-QPJJXVBHSA-N
  • InChI=1/C15H12O4/c16-12-8-5-10(6-9-12)4-7-11-2-1-3-13(17)14(11)15(18)19/h1-9,16-17H,(H,18,19)/b7-4+
    Key: UWXXIBUTKVUHTR-QPJJXVBHBH
  • Oc2ccc(cc2)\C=C\c(c1C(O)=O)cccc1O
Properties
C15H12O4
Molar mass 256.257 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Hydrangeic acid is a stilbenoid found in the leaves of Hydrangea macrophylla.[1]

Hydrangeic acid is being investigated as a possible antidiabetic drug as it significantly lowered blood glucose, triglyceride and free fatty acid levels in laboratory animals.[1]

See also

  • Lunularic acid, the corresponding dihydrostilbenoid also found in H. macrophylla

References

  1. ^ a b Hydrangeic acid from the processed leaves of Hydrangea macrophylla var. thunbergii as a new type of anti-diabetic compound. Hailong Zhang, Hisashi Matsuda, Chihiro Yamashita, Seikou Nakamura and Masayuki Yoshikawa, European Journal of Pharmacology, Volume 606, Issues 1–3, 15 March 2009, Pages 255–261, doi:10.1016/j.ejphar.2009.01.005
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