Wrench was educated at Repton School. He graduated M.B., B.S. in 1903 and M.D. in 1904 from London University.[2] He had several years experience of agrobiology in India.[3] Wrench was Assistant Master of Rotunda Hospital.[4][5]
Wrench's best known work was The Wheel of Health, a study of the nutritional research of Sir Robert McCarrison and of the Hunza people.[6][7][8] The book has been described as a "classic of the early organic movement."[9] It was dedicated to Lord Northbourne.[10] In 1939, Wrench published an article in the British Medical Journal on soil health and how it relates to human health.[11]
Wrench communicated with other early organic pioneers in Britain including Albert Howard and Gerard Wallop.[9] He died at his home in Karachi, Pakistan.[12]
^Brevik, E.C., J.J. Steffan, L.C. Burgess, and A. Cerdà. 2017. Links between soil security and the influence of soil on human health. In D. Field, C. Morgan, and A. McBratney (Eds.), Global Soil Security. Progress in Soil Science Series. Springer. pp. 261-274.