Osobor made an immediate impact as a freshman at Montana State, averaging six points and four rebounds per game.[4] The following season, he averaged ten points and five rebounds per game, being named the conference's top reserve.[5] He entered the transfer portal following his sophomore season.[6]
On May 2, 2023, Osobor announced that he would be transferring to Utah State University to play for the Aggies.[7] He began his junior season by being named the MVP of the Cayman Islands Classic.[8] During the season, Osobor emerged as the team's leading scorer.[9] He set a new career high with 32 points in an 88–60 win over Air Force on January 2, 2024.[10][11] Osobor was named the Mountain West Player of the Year and Newcomer of the Year, as well as being named first-team All-Mountain West.[12][13] He finished the season averaging 17.7 points, 9.0 rebounds and 2.8 blocks per game, before entering the transfer portal for a second time.[14][15] On May 13, 2024, he announced he would play his final season of college eligibility at Washington.[16]