Bermúdez made her professional debut on 22 October 2016, scoring a four-round unanimous decision (UD) victory against Adriana Moldonado at the Estadio cubierto Sub sede Cruce Alberdi in Rosario, Argentina.[2]
After compiling a record of 9–0 (2 KOs), she defeated Vanesa Lorena Taborda on 28 September 2018 at the Olimpico Football Club in Villa Gobernador Gálvez, Argentina, capturing the vacant South American super flyweight title via UD with the scorecards reading 100–90, 100–91.5 and 100–93.[3]
Her next fight came three months later on 29 December, moving down two weight classes to challenge IBF female junior flyweight champion Guadalupe Bautista at the Club Atlético Talleres in Villa Gobernador Gálvez. Bermúdez defeated Bautista via split decision (SD) to capture her first world title, with two judges scoring the bout 96–94 in favour of Bermúdez while the third scored it 96–94 to Bautista.[4] Bermúdez' sister, Daniela, also became a world champion on the same card, winning the WBO female bantamweight title.[5]
Bermudez added the WBO female light-flyweight World title to her collection with a fifth-round stoppage of Venezuela's Debora Rengifo on 26 March 2022.[6]
She lost her titles on 26 November 2022, going down to a majority decision defeat against Yokasta Valle from Costa Rica at Dignity Health Sports Park in Carson, California, USA.[7]
Three-weight world champion Valle opted to return to strawweight leading to Bermudez being given an immediate chance to regain both titles when she faced Mexico's Tania Enriquez at Estadio Luna Park in Buenos Aires, Argentina, on 10 March 2023. She won the fight by unanimous decision to become a two-time world champion.[8]
