Dinitolmide

Dinitolmide
Names
Preferred IUPAC name
2-Methyl-3,5-dinitrobenzamide
Other names
3,5-Dinitro-o-toluamide
Zoalene
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.005.189 Edit this at Wikidata
UNII
  • InChI=1S/C8H7N3O5/c1-4-6(8(9)12)2-5(10(13)14)3-7(4)11(15)16/h2-3H,1H3,(H2,9,12) checkY
    Key: ZEFNOZRLAWVAQF-UHFFFAOYSA-N checkY
  • InChI=1/C8H7N3O5/c1-4-6(8(9)12)2-5(10(13)14)3-7(4)11(15)16/h2-3H,1H3,(H2,9,12)
    Key: ZEFNOZRLAWVAQF-UHFFFAOYAL
  • O=[N+]([O-])c1cc(cc(C(=O)N)c1C)[N+]([O-])=O
Properties
C8H7N3O5
Molar mass 225.16 g/mol
Melting point 177 °C; 351 °F; 450 K[1]
Pharmacology
QP51AX12 (WHO)
Hazards
Flash point noncombustible[1]
NIOSH (US health exposure limits):
PEL (Permissible)
 none[1]
REL (Recommended)
 TWA 5 mg/m3[1]
IDLH (Immediate danger)
 N.D.[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Dinitolmide (or zoalene) is a fodder additive for poultry, used to prevent coccidiosis infections.[2] It is sold under trade names such as Coccidine A, Coccidot, and Zoamix.

Dinitolmide is usually added to feed in doses of 125 ppm (preventive) or 250 ppm (curative). It is a broad-spectrum anticoccidial drug,[2] preventing seven main strains of Eimeria coccidium. It leaves no residues in tissues.[citation needed] It can be also used to prevent coccidiosis of domestic rabbits.

References

  1. ^ a b c d e NIOSH Pocket Guide to Chemical Hazards. "#0230". National Institute for Occupational Safety and Health (NIOSH).
  2. ^ a b Gerhold, R. W.; Fuller, A. L.; Lollis, L.; Parr, C.; McDougald, L. R. (2011). "The Efficacy of Anticoccidial Products against Eimeria spp. in Northern Bobwhites". Avian Diseases. 55 (1): 59–64. doi:10.1637/9572-101310-Reg.1. PMID 21500637. S2CID 30943649.
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