Dimethylglycine N-methyltransferase

Dimethylglycine N-methyltransferase
Identifiers
EC no.	2.1.1.161
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Dimethylglycine N-methyltransferase (EC 2.1.1.161, BsmB, DMT) is an enzyme with systematic name S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase (betaine-forming).[1] This enzyme catalyses the following chemical reaction

S-adenosyl-L-methionine + N,N-dimethylglycine ${\displaystyle \rightleftharpoons }$ S-adenosyl-L-homocysteine + betaine

This enzyme is purified from the marine cyanobacterium Synechococcus sp. WH8102.

References

1. Lu WD, Chi ZM, Su CD (December 2006). "Identification of glycine betaine as compatible solute in Synechococcus sp. WH8102 and characterization of its N-methyltransferase genes involved in betaine synthesis". Archives of Microbiology. 186 (6): 495–506. doi:10.1007/s00203-006-0167-8. PMID 17019606. S2CID 25210214.

External links

• Dimethylglycine+N-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)