Cirsilineol

Cirsilineol
Names
IUPAC name
4′,5-Dihydroxy-3′,6,7-trimethoxyflavone
Systematic IUPAC name
5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,7-dimethoxy-4H-1-benzopyran-4-one
Other names
Eupatrin
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
UNII
  • InChI=1S/C18H16O7/c1-22-13-6-9(4-5-10(13)19)12-7-11(20)16-14(25-12)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3
    Key: VKOSQMWSWLZQPA-UHFFFAOYSA-N
  • InChI=1S/C18H16O7/c1-22-13-6-9(4-5-10(13)19)12-7-11(20)16-14(25-12)8-15(23-2)18(24-3)17(16)21/h4-8,19,21H,1-3H3
    Key: VKOSQMWSWLZQPA-UHFFFAOYSA-N
  • COC1=C(C=CC(=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)OC)OC)O)O
Properties
C18H16O7
Molar mass 344.319 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Cirsilineol is a bioactive flavone isolated from Artemisia[1] and from Teucrium gnaphalodes.[2]

References

  1. ^ Sheng, X; Sun, Y; Yin, Y; Chen, T; Xu, Q (2008). "Cirsilineol inhibits proliferation of cancer cells by inducing apoptosis via mitochondrial pathway". The Journal of Pharmacy and Pharmacology. 60 (11): 1523–9. doi:10.1211/jpp/60.11.0014. PMID 18957174.
  2. ^ Flavonoid Aglycones and Glycosides from Teucrium gnaphalodes. F. A. T. Barberán, M. I. Gil, F. Tomás, F. Ferreres and A. Arques, J. Nat. Prod., 1985, 48 (5), pages 859–860, doi:10.1021/np50041a040


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