Beta-amyrin 24-hydroxylase

Beta-amyrin 24-hydroxylase
Identifiers
EC no.	1.14.99.43
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Beta-amyrin 24-hydroxylase (EC 1.14.99.43, sophoradiol 24-hydroxylase, CYP93E1) is an enzyme with systematic name beta-amyrin,AH2:oxygen oxidoreductase (24-hydroxylating).[1] This enzyme catalyses the following chemical reaction

(1) beta-amyrin + AH₂ + O₂ ${\displaystyle \rightleftharpoons }$ 24-hydroxy-beta-amyrin + A + H₂O

(2) sophoradiol + AH₂ + O₂ ${\displaystyle \rightleftharpoons }$ 24-hydroxysophoradiol + A + H₂O

Beta-amyrin 24-hydroxylase is heme-thiolate protein (P-450).

References

1. Shibuya M, Hoshino M, Katsube Y, Hayashi H, Kushiro T, Ebizuka Y (March 2006). "Identification of beta-amyrin and sophoradiol 24-hydroxylase by expressed sequence tag mining and functional expression assay". The FEBS Journal. 273 (5): 948–59. doi:10.1111/j.1742-4658.2006.05120.x. PMID 16478469.

External links

• Beta-amyrin+24-hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)