9,9'-Dicis-zeta-carotene desaturase

9,9'-dicis-zeta-carotene desaturase
Identifiers
EC no.	1.3.5.6
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

9,9'-dicis-zeta-carotene desaturase (EC 1.3.5.6, zeta-carotene desaturase, ZDS) is an enzyme with systematic name 9,9'-dicis-zeta-corotene:quinone oxidoreductase.[1][2][3][4] This enzyme catalyses the following chemical reaction

9,9'-dicis-zeta-carotene + 2 quinone ${\displaystyle \rightleftharpoons }$ 7,9,7',9'-tetracis-lycopene + 2 quinol (overall reaction)

(1a) 9,9'-dicis-zeta-carotene + a quinone ${\displaystyle \rightleftharpoons }$ 7,9,9'-tricis-neurosporene + a quinol

(1b) 7,9,9'-tricis-neurosporene + a quinone ${\displaystyle \rightleftharpoons }$ 7,9,7',9'-tetracis-lycopene + a quinol

This enzyme is involved in carotenoid biosynthesis in plants and cyanobacteria.

References

1. Albrecht M, Linden H, Sandmann G (February 1996). "Biochemical characterization of purified zeta-carotene desaturase from Anabaena PCC 7120 after expression in Escherichia coli". European Journal of Biochemistry. 236 (1): 115–20. doi:10.1111/j.1432-1033.1996.00115.x. PMID 8617254.
2. Josse EM, Simkin AJ, Gaffé J, Labouré AM, Kuntz M, Carol P (August 2000). "A plastid terminal oxidase associated with carotenoid desaturation during chromoplast differentiation". Plant Physiology. 123 (4): 1427–36. doi:10.1104/pp.123.4.1427. PMC 59099. PMID 10938359.
3. Breitenbach J, Kuntz M, Takaichi S, Sandmann G (October 1999). "Catalytic properties of an expressed and purified higher plant type zeta-carotene desaturase from Capsicum annuum". European Journal of Biochemistry. 265 (1): 376–83. doi:10.1046/j.1432-1327.1999.00746.x. PMID 10491195.
4. Breitenbach J, Sandmann G (March 2005). "zeta-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene". Planta. 220 (5): 785–93. doi:10.1007/s00425-004-1395-2. PMID 15503129. S2CID 23793453.

External links

• 9,9'-dicis-zeta-carotene+desaturase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)