Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
Stadium: Morumbi Attendance: 46,378 Referee: Douglas Marques das Flores
Note: The match against São Paulo, originally scheduled for the 6 February, was postponed to 10 March, due to the Palmeiras participation in the 2021 FIFA Club World Cup.
Source: CBF Rules for classification: 1) points; 2) wins; 3) goal difference; 4) goals scored; 5) head-to-head results (only between two teams); 6) fewest red cards; 7) fewest yellow cards; 8) drawing of lots. (C) Champions Notes:
^Flamengo qualified for the Copa Libertadores group stage by winning the 2022 Copa Libertadores. Since they also won the 2022 Copa do Brasil, the berth awarded to the Copa do Brasil champions (Copa Libertadores group stage) was passed over to the league's best placed team not already qualified.
The draw for the round of 16 was held on 7 June 2022 at CBF headquarters in Rio de Janeiro.[26] The order of the matches were announced later on the same day.